ecps-1 Proteasome component Ecm29 N-terminal domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: ecps-1
Official Full Name: Proteasome component Ecm29 N-terminal domain-containing protein
Primary source: WormBase:WBGene00008422
Locus tag: CELE_D2045.2
See related: AllianceGenome:WB:WBGene00008422
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable molecular adaptor activity. Predicted to be involved in ERAD pathway. Predicted to be part of proteasome complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human ECPAS (Ecm29 proteasome adaptor and scaffold). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ecps-1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 17

Sequence:: Chromosome: III; NC_003281.10 (10452753..10460551, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

H04D03.3 (e-PCR)
- UniSTS:311316

D2045.2 (e-PCR)
- UniSTS:309485

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables molecular adaptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables molecular adaptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ERAD pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in proteasome assembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Proteasome component Ecm29 N-terminal domain-containing protein

NP_499306.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

10452753..10460551 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066905.4 → NP_499306.2 Proteasome component Ecm29 N-terminal domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_499306.2

Status: REVIEWED

UniProtKB/TrEMBL

Q18983

Conserved Domains (2) summary

pfam13001
Location:25 → 512

Ecm29; Proteasome stabilizer

sd00044
Location:1054 → 1083

HEAT; HEAT repeat [structural motif]