C02F5.3 putative GTP-binding protein C02F5.3 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: C02F5.3
Official Full Name: putative GTP-binding protein C02F5.3
Primary source: WormBase:WBGene00015346
Locus tag: CELE_C02F5.3
See related: AllianceGenome:WB:WBGene00015346
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable GTP binding activity. Predicted to be involved in cytoplasmic translation. Predicted to be active in cytoplasm. Orthologous to human DRG2 (developmentally regulated GTP binding protein 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See C02F5.3 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 3

Sequence:: Chromosome: III; NC_003281.10 (8245891..8247258)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C02F5.3 (e-PCR)
- UniSTS:308893

C02F5.4 (e-PCR)
- UniSTS:308430

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cytoplasmic translation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative GTP-binding protein C02F5.3

NP_498808.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

8245891..8247258

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066407.6 → NP_498808.2 putative GTP-binding protein C02F5.3 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498808.2

Status: REVIEWED

UniProtKB/Swiss-Prot

P34280

Conserved Domains (4) summary

cd01666
Location:289 → 365

TGS_DRG_C; TGS_DRG_C: DRG (developmentally regulated GTP-binding protein) represents a family of GTP-binding proteins that includes two members, DRG1 and DRG2. DRG1 and DRG2 have a C-terminal TGS domain (named after the ThrRS, GTPase, and SpoT proteins where it ...

cd01896
Location:63 → 295

DRG; Developmentally Regulated GTP-binding protein (DRG)

COG1163
Location:1 → 366

Rbg1; Ribosome-interacting GTPase 1 [Translation, ribosomal structure and biogenesis]

cl21455
Location:3 → 97

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases