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kcmf-1 Drought induced 19 protein type zinc-binding domain-containing protein;zf-Di19 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 176095, updated on 4-Jan-2025

Summary

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Official Symbol
kcmf-1
Official Full Name
Drought induced 19 protein type zinc-binding domain-containing protein;zf-Di19 domain-containing protein
Primary source
WormBase:WBGene00022785
Locus tag
CELE_ZK652.6
See related
AllianceGenome:WB:WBGene00022785
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in synaptic signaling. Predicted to be located in nucleus and synapse. Predicted to be active in plasma membrane. Orthologous to human KCMF1 (potassium channel modulatory factor 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See kcmf-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
9
Sequence:
Chromosome: III; NC_003281.10 (7829411..7832494)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Eukaryotic translation initiation factor 3 subunit A Neighboring gene Homeobox protein ceh-23 Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of cell communication IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of signaling IEA
Inferred from Electronic Annotation
more info
  
involved_in synaptic signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in synapse IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Drought induced 19 protein type zinc-binding domain-containing protein;zf-Di19 domain-containing protein
NP_001023028.2
  • Confirmed by transcript evidence
NP_001299933.1
  • Confirmed by transcript evidence
NP_001299934.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7829411..7832494
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027857.6 → NP_001023028.2  zf-Di19 domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34664, Q7Z143
    Conserved Domains (2) summary
    cd02338
    Location:12 → 68
    ZZ_PCMF_like; Zinc finger, ZZ type. Zinc finger present in potassium channel modulatory factor (PCMF) 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Human potassium channel ...
    pfam05605
    Location:93 → 130
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding

  2. NM_001313004.3 → NP_001299933.1  Drought induced 19 protein type zinc-binding domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34664, Q7Z143
    UniProtKB/TrEMBL
    A0A0K3AS04
    Conserved Domains (1) summary
    pfam05605
    Location:29 → 66
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding

  3. NM_001313005.3 → NP_001299934.1  zf-Di19 domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3AUB7

RNA

  1. NR_132453.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
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