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pcp-1 Putative serine protease pcp-1 [ Caenorhabditis elegans ]

Gene ID: 176086, updated on 4-Jan-2025

Summary

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Official Symbol
pcp-1
Official Full Name
Putative serine protease pcp-1
Primary source
WormBase:WBGene00003956
Locus tag
CELE_ZK112.1
See related
AllianceGenome:WB:WBGene00003956
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Is expressed in intestine. Orthologous to human PRCP (prolylcarboxypeptidase). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See pcp-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (7758903..7761262)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene B box-type domain-containing protein;B-box type zinc finger protein ncl-1;RING-type E3 ubiquitin transferase Neighboring gene AMP-binding domain-containing protein Neighboring gene Cadherin-3 Neighboring gene ncRNA Neighboring gene Metaxin-2 homolog Neighboring gene Putative ATP-dependent RNA helicase ZK686.2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Improved Biocompatibility of Amino-Functionalized Graphene Oxide in Caenorhabditis elegans. Rive C, et al. Small, 2019 Nov. PMID 31576668
  2. SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells. Jackson J, et al. Mol Metab, 2022 Jul. PMID 35452878, Free PMC Article
  3. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
  4. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
  5. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables dipeptidyl-peptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type exopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Putative serine protease pcp-1
NP_498688.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7758903..7761262
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066287.7 → NP_498688.1  Putative serine protease pcp-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498688.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34610
    Conserved Domains (1) summary
    cl21494
    Location:50 → 498
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34610.2

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