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F56C9.10 BCAS3 WD40 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 176040, updated on 4-Jan-2025

Summary

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Official Symbol
F56C9.10
Official Full Name
BCAS3 WD40 domain-containing protein
Primary source
WormBase:WBGene00018953
Locus tag
CELE_F56C9.10
See related
AllianceGenome:WB:WBGene00018953
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in response to starvation. Predicted to be active in cytoplasm. Is expressed in anal depressor muscle; body wall musculature; and nervous system. Human ortholog(s) of this gene implicated in Hengel-Maroofian-Schols syndrome. Orthologous to human BCAS3 (BCAS3 microtubule associated cell migration factor). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See F56C9.10 in Genome Data Viewer
Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (7329705..7335316, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Secreted protein Neighboring gene Long Arms of the Bivalent protein Neighboring gene Serine/threonine-protein phosphatase PP1-beta Neighboring gene ncRNA Neighboring gene Kinesin-associated protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
  2. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in autophagy IEA
Inferred from Electronic Annotation
more info
  
involved_in response to starvation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
BCAS3 WD40 domain-containing protein
NP_001360481.1
  • Confirmed by transcript evidence
NP_001360482.1
  • Confirmed by transcript evidence
NP_741222.1
  • Confirmed by transcript evidence
NP_741223.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7329705..7335316 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171190.6 → NP_741222.1  BCAS3 WD40 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741222.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KY88

  2. NM_001372620.3 → NP_001360482.1  BCAS3 WD40 domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A486WY26

  3. NM_001372619.3 → NP_001360481.1  BCAS3 WD40 domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A486WX46

  4. NM_171882.6 → NP_741223.1  BCAS3 WD40 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741223.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MQ22
Nucleotide Protein
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