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F20H11.4 Protein-tyrosine phosphatase [ Caenorhabditis elegans ]

Gene ID: 175937, updated on 2-Nov-2024

Summary

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Official Symbol
F20H11.4
Official Full Name
Protein-tyrosine phosphatase
Primary source
WormBase:WBGene00017647
Locus tag
CELE_F20H11.4
See related
AllianceGenome:WB:WBGene00017647
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in motor neuron axon guidance and signal transduction. Is expressed in nervous system and pharynx. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F20H11.4 in Genome Data Viewer
Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (6608622..6610455)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Protein strawberry notch homolog Neighboring gene Malate dehydrogenase, mitochondrial Neighboring gene Serpentine Receptor, class T Neighboring gene Carboxypeptidase Neighboring gene Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in motor neuron axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Protein-tyrosine phosphatase
NP_498458.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    6608622..6610455
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066057.4 → NP_498458.1  Protein-tyrosine phosphatase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498458.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01736
    Conserved Domains (2) summary
    cd00047
    Location:144 → 375
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam00102
    Location:142 → 375
    Y_phosphatase; Protein-tyrosine phosphatase
Nucleotide Protein
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Gene LinkOut

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