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akap-1 KH domain-containing protein akap-1;Tudor domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 175898, updated on 4-Jan-2025

Summary

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Official Symbol
akap-1
Official Full Name
KH domain-containing protein akap-1;Tudor domain-containing protein
Primary source
WormBase:WBGene00016977
Locus tag
CELE_C56G2.1
See related
AllianceGenome:WB:WBGene00016977
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA binding activity. Predicted to be located in membrane and mitochondrion. Is expressed in several structures, including gonad. Orthologous to human AKAP1 (A-kinase anchoring protein 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See akap-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
16
Sequence:
Chromosome: III; NC_003281.10 (6353384..6366661)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene tRNA MethylTransferase Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene N-acetyltransferase domain-containing protein Neighboring gene THO complex subunit 2 Neighboring gene ncRNA Neighboring gene Small ribosomal subunit protein uS15

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs. Hayes GD, et al. Cold Spring Harb Symp Quant Biol, 2006. PMID 17381276
  2. Conserved RNA-binding proteins required for dendrite morphogenesis in Caenorhabditis elegans sensory neurons. Antonacci S, et al. G3 (Bethesda), 2015 Feb 10. PMID 25673135, Free PMC Article
  3. Lifespan regulation by evolutionarily conserved genes essential for viability. Curran SP, et al. PLoS Genet, 2007 Apr 6. PMID 17411345, Free PMC Article
  4. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
  5. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
KH domain-containing protein akap-1;Tudor domain-containing protein
NP_001348742.1
  • Confirmed by transcript evidence
NP_001348743.1
  • Confirmed by transcript evidence
NP_001348744.1
  • Confirmed by transcript evidence
NP_001370528.1
  • Confirmed by transcript evidence
NP_741191.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    6353384..6366661
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001382893.2 → NP_001370528.1  KH domain-containing protein akap-1 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09285, Q09286
    Conserved Domains (4) summary
    PTZ00121
    Location:183 → 477
    PTZ00121; MAEBL; Provisional
    cd20407
    Location:686 → 761
    Tudor_AKAP1; Tudor domain found in mitochondrial A-kinase anchor protein 1 (AKAP1) and similar proteins
    NF033930
    Location:181 → 328
    pneumo_PspA; pneumococcal surface protein A
    cd22395
    Location:530 → 600
    KH-I_AKAP1; type I K homology (KH) RNA-binding domain found in mitochondrial A-kinase anchor protein 1 (AKAP1) and similar proteins

  2. NM_001361723.3 → NP_001348743.1  Tudor domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2K5ATV3
    Conserved Domains (3) summary
    pfam00013
    Location:525 → 590
    KH_1; KH domain
    pfam00567
    Location:635 → 751
    TUDOR; Tudor domain
    pfam16001
    Location:193 → 350
    DUF4775; Domain of unknown function (DUF4775)

  3. NM_001361724.3 → NP_001348742.1  Tudor domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2K5ATU1
    Conserved Domains (3) summary
    pfam00013
    Location:511 → 576
    KH_1; KH domain
    pfam00567
    Location:621 → 737
    TUDOR; Tudor domain
    pfam16001
    Location:193 → 350
    DUF4775; Domain of unknown function (DUF4775)

  4. NM_001361725.3 → NP_001348744.1  Tudor domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2K5ATU5
    Conserved Domains (3) summary
    pfam00013
    Location:431 → 496
    KH_1; KH domain
    pfam00567
    Location:541 → 657
    TUDOR; Tudor domain
    pfam16001
    Location:93 → 256
    DUF4775; Domain of unknown function (DUF4775)

  5. NM_171164.7 → NP_741191.1  KH domain-containing protein akap-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741191.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09285
    Conserved Domains (3) summary
    smart00333
    Location:235 → 286
    TUDOR; Tudor domain
    pfam00013
    Location:73 → 137
    KH_1; KH domain
    pfam00567
    Location:176 → 300
    TUDOR; Tudor domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q09285.2

Gene LinkOut

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