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hpo-10 SAC3/GANP/THP3 conserved domain-containing protein;SAC3_GANP domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 175829, updated on 2-Nov-2024

Summary

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Official Symbol
hpo-10
Official Full Name
SAC3/GANP/THP3 conserved domain-containing protein;SAC3_GANP domain-containing protein
Primary source
WormBase:WBGene00017158
Locus tag
CELE_F01F1.1
See related
AllianceGenome:WB:WBGene00017158
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be active in nucleus. Is expressed widely. Orthologous to human LENG8 (leukocyte receptor cluster member 8). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See hpo-10 in Genome Data Viewer
Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (5879489..5882430)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Abnormal cell migration protein 21 Neighboring gene ncRNA Neighboring gene COX assembly mitochondrial protein Neighboring gene Uncharacterized protein Neighboring gene ShKT domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans. Wang L, et al. Protein Cell, 2016 Oct. PMID 27638466, Free PMC Article
  2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SAC3/GANP/THP3 conserved domain-containing protein;SAC3_GANP domain-containing protein
NP_001370504.1
  • Confirmed by transcript evidence
NP_001379733.1
  • Confirmed by transcript evidence
NP_498274.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    5879489..5882430
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001382886.1 → NP_001370504.1  SAC3_GANP domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95QN0

  2. NM_065873.5 → NP_498274.1  SAC3/GANP/THP3 conserved domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498274.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZ29
    Conserved Domains (1) summary
    pfam03399
    Location:418 → 612
    SAC3_GANP; SAC3/GANP/Nin1/mts3/eIF-3 p25 family

  3. NM_001392113.1 → NP_001379733.1  SAC3/GANP/THP3 conserved domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8I7L2
    Conserved Domains (1) summary
    cl24019
    Location:404 → 620
    CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family
Nucleotide Protein
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