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tmem-131 Transmembrane protein 131 homolog [ Caenorhabditis elegans ]

Gene ID: 175677, updated on 2-Nov-2024

Summary

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Official Symbol
tmem-131
Official Full Name
Transmembrane protein 131 homolog
Primary source
WormBase:WBGene00016170
Locus tag
CELE_C27F2.8
See related
AllianceGenome:WB:WBGene00016170
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Located in endoplasmic reticulum membrane. Is expressed in hypodermis; intestine; and neurons. Orthologous to human TMEM131 (transmembrane protein 131). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tmem-131 in Genome Data Viewer
Location:
chromosome: III
Exon count:
15
Sequence:
Chromosome: III; NC_003281.10 (4991439..4998161, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene putative F-box protein C27F2.7 Neighboring gene PCI domain-containing protein 2 homolog Neighboring gene WD Repeat protein Neighboring gene Guanine nucleotide exchange protein smcr-8 Neighboring gene Coiled-coil domain-containing protein 25 Neighboring gene Transmembrane protein 144 homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking. Zhang Z, et al. Sci Adv, 2020 Feb. PMID 32095531, Free PMC Article
  2. The conserved transmembrane protein TMEM-39 coordinates with COPII to promote collagen secretion and regulate ER stress response. Zhang Z, et al. PLoS Genet, 2021 Feb. PMID 33524011, Free PMC Article
  3. A global analysis of genetic interactions in Caenorhabditis elegans. Byrne AB, et al. J Biol, 2007. PMID 17897480, Free PMC Article
  4. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Transmembrane protein 131 homolog
NP_498059.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    4991439..4998161 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065658.8 → NP_498059.2  Transmembrane protein 131 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498059.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G4S3K6, Q18264
    Conserved Domains (4) summary
    pfam04747
    Location:1368 → 1528
    DUF612; Protein of unknown function, DUF612
    pfam05109
    Location:1390 → 1818
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam09507
    Location:1220 → 1485
    CDC27; DNA polymerase subunit Cdc27
    pfam12371
    Location:117 → 199
    TMEM131_like; Transmembrane protein 131-like
Nucleotide Protein
Heading Accession and Version

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