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ppat-1 Amidophosphoribosyltransferase [ Caenorhabditis elegans ]

Gene ID: 175613, updated on 2-Nov-2024

Summary

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Official Symbol
ppat-1
Official Full Name
Amidophosphoribosyltransferase
Primary source
WormBase:WBGene00011407
Locus tag
CELE_T04A8.5
See related
AllianceGenome:WB:WBGene00011407
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable amidophosphoribosyltransferase activity. Predicted to be involved in purine nucleotide biosynthetic process. Is expressed in intestine. Orthologous to human PPAT (phosphoribosyl pyrophosphate amidotransferase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ppat-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (4689280..4692171)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Costars domain-containing protein Neighboring gene ncRNA Neighboring gene RRM domain-containing protein Neighboring gene Rad60/SUMO-like domain-containing protein Neighboring gene 1,4-alpha-glucan branching enzyme

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables amidophosphoribosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables amidophosphoribosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in 'de novo' IMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in purine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in purine nucleotide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in purine nucleotide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Amidophosphoribosyltransferase
NP_497958.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    4689280..4692171
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065557.8 → NP_497958.1  Amidophosphoribosyltransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497958.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22134
    Conserved Domains (3) summary
    cd06223
    Location:293 → 415
    PRTases_typeI; Phosphoribosyl transferase (PRT)-type I domain
    COG0034
    Location:1 → 478
    PurF; Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]
    cd00715
    Location:2 → 277
    GPATase_N; Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the ...
Nucleotide Protein
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