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gip-1 Gamma-tubulin complex component [ Caenorhabditis elegans ]

Gene ID: 175355, updated on 9-Dec-2024

Summary

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Official Symbol
gip-1
Official Full Name
Gamma-tubulin complex component
Primary source
WormBase:WBGene00001589
Locus tag
CELE_H04J21.3
See related
AllianceGenome:WB:WBGene00001589
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable gamma-tubulin binding activity. Predicted to contribute to microtubule minus-end binding activity. Predicted to be involved in meiotic cell cycle; microtubule cytoskeleton organization; and mitotic cell cycle. Predicted to be located in cytoplasm; membrane; and microtubule cytoskeleton. Predicted to be part of gamma-tubulin complex. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See gip-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
14
Sequence:
Chromosome: III; NC_003281.10 (2347591..2362056)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene PPM-type phosphatase domain-containing protein Neighboring gene PHD finger-like domain-containing protein 5A Neighboring gene Serpentine Receptor, class D (Delta) Neighboring gene Ubiquitin-like domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Tissue-specific degradation of essential centrosome components reveals distinct microtubule populations at microtubule organizing centers. Sallee MD, et al. PLoS Biol, 2018 Aug. PMID 30080857, Free PMC Article
  2. The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent. Hannak E, et al. J Cell Biol, 2002 May 13. PMID 12011109, Free PMC Article
  3. Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans. Hannak E, et al. J Cell Biol, 2001 Dec 24. PMID 11748251, Free PMC Article
  4. Katanin controls mitotic and meiotic spindle length. McNally K, et al. J Cell Biol, 2006 Dec 18. PMID 17178907, Free PMC Article
  5. PTRN-1 (CAMSAP) and NOCA-2 (NINEIN) are required for microtubule polarity in Caenorhabditis elegans dendrites. He L, et al. PLoS Biol, 2022 Nov. PMID 36395330, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables gamma-tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables gamma-tubulin binding IEA
Inferred from Electronic Annotation
more info
  
contributes_to microtubule minus-end binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic microtubule organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in meiotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
involved_in microtubule nucleation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule nucleation IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
part_of gamma-tubulin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule organizing center IEA
Inferred from Electronic Annotation
more info
  
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Gamma-tubulin complex component
NP_001022632.1
  • Confirmed by transcript evidence
NP_497540.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    2347591..2362056
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027461.4 → NP_001022632.1  Gamma-tubulin complex component [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022632.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O61208, Q8MTJ4
    Conserved Domains (1) summary
    pfam04130
    Location:305 → 636
    Spc97_Spc98; Spc97 / Spc98 family

  2. NM_065139.8 → NP_497540.3  Gamma-tubulin complex component [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497540.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8ITY3
    Conserved Domains (1) summary
    pfam04130
    Location:305 → 636
    Spc97_Spc98; Spc97 / Spc98 family
Nucleotide Protein
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