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dpy-1 VWFA domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 175342, updated on 4-Jan-2025

Summary

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Official Symbol
dpy-1
Official Full Name
VWFA domain-containing protein
Primary source
WormBase:WBGene00001063
Locus tag
CELE_M01E10.2
See related
AllianceGenome:WB:WBGene00001063
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in body morphogenesis and regulation of growth. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See dpy-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
20
Sequence:
Chromosome: III; NC_003281.10 (2034988..2048007, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene tRNA-Glu Neighboring gene ncRNA Neighboring gene tRNA-Glu Neighboring gene ncRNA Neighboring gene ATS3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of larval growth in C. elegans cuticle mutants. Nyaanga J, et al. MicroPubl Biol, 2022. PMID 36411799, Free PMC Article
  2. Isolation and mapping of DNA probes within the linkage group I gene cluster of Caenorhabditis elegans. Starr T, et al. Genome, 1989 Jun. PMID 2744447
  3. UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans. Leung-Hagesteijn C, et al. Cell, 1992 Oct 16. PMID 1384987
  4. Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity. Ewald CY, et al. Nature, 2015 Mar 5. PMID 25517099, Free PMC Article
  5. The genetic and RFLP characterization of the left end of linkage group III in Caenorhabditis elegans. Pilgrim D. Genome, 1993 Aug. PMID 8104844

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in body morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of multicellular organism growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
VWFA domain-containing protein
NP_001367968.1
  • Confirmed by transcript evidence
NP_001370799.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    2034988..2048007 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001384037.2 → NP_001370799.1  VWFA domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G4SNP7
    Conserved Domains (2) summary
    pfam00092
    Location:823 → 975
    VWA; von Willebrand factor type A domain
    cl27758
    Location:1050 → 1299
    Zona_pellucida; Zona pellucida-like domain

  2. NM_001381759.2 → NP_001367968.1  VWFA domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9TXR6
    Conserved Domains (2) summary
    smart00241
    Location:717 → 966
    ZP; Zona pellucida (ZP) domain
    pfam00092
    Location:490 → 642
    VWA; von Willebrand factor type A domain
Nucleotide Protein
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