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kbp-4 KNL (kinetochore null) Binding Protein [ Caenorhabditis elegans ]

Gene ID: 175273, updated on 9-Dec-2024

Summary

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Official Symbol
kbp-4
Official Full Name
KNL (kinetochore null) Binding Protein
Primary source
WormBase:WBGene00022357
Locus tag
CELE_Y92C3B.1
See related
AllianceGenome:WB:WBGene00022357
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Located in kinetochore. Part of Ndc80 complex. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See kbp-4 in Genome Data Viewer
Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003281.10 (1080901..1081300)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Splicing factor U2AF 65 kDa subunit Neighboring gene ncRNA Neighboring gene Ras-related protein Rab-18 Neighboring gene RING-type domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Small RNA-Catalytic Argonaute Pathway Tunes Germline Transcript Levels to Ensure Embryonic Divisions. Gerson-Gurwitz A, et al. Cell, 2016 Apr 7. PMID 27020753, Free PMC Article
  2. The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cheeseman IM, et al. Cell, 2006 Dec 1. PMID 17129783
  3. Crosstalk between microtubule attachment complexes ensures accurate chromosome segregation. Cheerambathur DK, et al. Science, 2013 Dec 6. PMID 24231804, Free PMC Article
  4. Kinetochores: if you build it, they will come. DeLuca JG, et al. Curr Biol, 2004 Nov 9. PMID 15530383
  5. SPDL-1 functions as a kinetochore receptor for MDF-1 in Caenorhabditis elegans. Yamamoto TG, et al. J Cell Biol, 2008 Oct 20. PMID 18936247, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
part_of Ndc80 complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in kinetochore IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
KNL (kinetochore null) Binding Protein
NP_497330.2
  • Product from WormBase gene class kbp;
    Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    1080901..1081300
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064929.8 → NP_497330.2  KNL (kinetochore null) Binding Protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497330.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N2X3
Nucleotide Protein
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