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elf-1 ETS domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 175226, updated on 2-Nov-2024

Summary

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Official Symbol
elf-1
Official Full Name
ETS domain-containing protein
Primary source
WormBase:WBGene00016029
Locus tag
CELE_C24A1.2
See related
AllianceGenome:WB:WBGene00016029
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in gonad development and regulation of cell division. Predicted to be active in nucleus. Is expressed in head neurons and pharynx. Orthologous to human ELF1 (E74 like ETS transcription factor 1); ELF2 (E74 like ETS transcription factor 2); and ELF4 (E74 like ETS transcription factor 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See elf-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (689169..715822)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene G protein-coupled receptor kinase 2 Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene Protein kinase domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene VPSAGDMMVRF-amide Neighboring gene Protein pat-12 Neighboring gene SXP/RAL-2 family protein Ani s 5-like cation-binding domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cyclin D regulation of a sexually dimorphic asymmetric cell division. Tilmann C, et al. Dev Cell, 2005 Oct. PMID 16198291, Free PMC Article
  2. Gene regulatory logic of dopamine neuron differentiation. Flames N, et al. Nature, 2009 Apr 16. PMID 19287374, Free PMC Article
  3. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
  4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in gonad development IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of cell division IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ETS domain-containing protein
NP_001021180.1
  • Confirmed by transcript evidence
NP_001021181.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    689169..715822
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001026010.5 → NP_001021181.1  ETS domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021181.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G4RYC9, Q400M2
    Conserved Domains (1) summary
    smart00413
    Location:293 → 379
    ETS; erythroblast transformation specific domain

  2. NM_001026009.3 → NP_001021180.1  ETS domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021180.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KYY1
    Conserved Domains (1) summary
    smart00413
    Location:294 → 380
    ETS; erythroblast transformation specific domain
Nucleotide Protein
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