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clec-66 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 174929, updated on 2-Nov-2024

Summary

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Official Symbol
clec-66
Official Full Name
C-type lectin domain-containing protein
Primary source
WormBase:WBGene00009397
Locus tag
CELE_F35C5.9
See related
AllianceGenome:WB:WBGene00009397
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in innate immune response. Is expressed in intestine. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See clec-66 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (12904398..12906644)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene VWFA domain-containing protein Neighboring gene C-type lectin domain-containing protein Neighboring gene Secreted protein Neighboring gene Protein sleepless Neighboring gene Knottin scorpion toxin-like domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress. Li TY, et al. Nat Aging, 2021 Feb. PMID 33718883, Free PMC Article
  2. Specificity of the innate immune system and diversity of C-type lectin domain (CTLD) proteins in the nematode Caenorhabditis elegans. Schulenburg H, et al. Immunobiology, 2008. PMID 18406370
  3. Transcriptome analyses describe the consequences of persistent HIF-1 over-activation in Caenorhabditis elegans. Feng D, et al. PLoS One, 2024. PMID 38517909, Free PMC Article
  4. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in innate immune response HEP PubMed 

General protein information

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Preferred Names
C-type lectin domain-containing protein
NP_496746.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    12904398..12906644
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064345.6 → NP_496746.1  C-type lectin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496746.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45445
    Conserved Domains (2) summary
    smart00034
    Location:243 → 382
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
    cd01477
    Location:36 → 223
    vWA_F09G8-8_type; VWA F09G8.8 type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b ...
Nucleotide Protein
Heading Accession and Version

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