lec-2 Galectin;Galectin domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: lec-2
Official Full Name: Galectin;Galectin domain-containing protein
Primary source: WormBase:WBGene00002265
Locus tag: CELE_F52H3.7
See related: AllianceGenome:WB:WBGene00002265
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable carbohydrate binding activity and galactoside binding activity. Located in membrane raft and plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See lec-2 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 8

Sequence:: Chromosome: II; NC_003280.10 (10009608..10016183, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

STS2-180 (e-PCR)
- UniSTS:241852

F52H3.7 (e-PCR)
- UniSTS:321495

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables carbohydrate binding	IBA Inferred from Biological aspect of Ancestor more info
enables carbohydrate binding	IEA Inferred from Electronic Annotation more info
enables galactoside binding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane raft	HDA more info	PubMed
located_in plasma membrane	HDA more info	PubMed

General protein information

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Preferred Names: Galectin;Galectin domain-containing protein

NP_001379091.1

Confirmed by transcript evidence

NP_001379290.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

10009608..10016183 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001393173.1 → NP_001379091.1 Galectin domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

Q20684

Conserved Domains (4) summary

smart00276
Location:978 → 1108

GLECT; Galectin

PRK10811
Location:474 → 771

rne; ribonuclease E; Reviewed

PRK14949
Location:235 → 662

PRK14949; DNA polymerase III subunits gamma and tau; Provisional

cd00070
Location:1116 → 1243

GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...
NM_001393174.1 → NP_001379290.1 Galectin [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

G5EGB1

Conserved Domains (1) summary

cd00070
Location:149 → 276

GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...