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M05D6.5 HIG1 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 174357, updated on 9-Dec-2024

Summary

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Official Symbol
M05D6.5
Official Full Name
HIG1 domain-containing protein
Primary source
WormBase:WBGene00010878
Locus tag
CELE_M05D6.5
See related
AllianceGenome:WB:WBGene00010878
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in mitochondrial respirasome assembly. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See M05D6.5 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (8480487..8482203, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Protein kinase domain-containing protein Neighboring gene Tyrosine-protein phosphatase domain-containing protein Neighboring gene Beta-lactamase-related domain-containing protein Neighboring gene TAil-Anchored Protein Neighboring gene Trimethyllysine dioxygenase, mitochondrial Neighboring gene Receptor-type tyrosine-protein phosphatase kappa;Receptor-type tyrosine-protein phosphatase mu;Tyrosine-protein phosphatase domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rcf1 and Rcf2, members of the hypoxia-induced gene 1 protein family, are critical components of the mitochondrial cytochrome bc1-cytochrome c oxidase supercomplex. Strogolova V, et al. Mol Cell Biol, 2012 Apr. PMID 22310663, Free PMC Article
  2. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
  3. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
  4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in mitochondrial respirasome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
HIG1 domain-containing protein
NP_001254151.1
  • Confirmed by transcript evidence
NP_001367209.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    8480487..8482203 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001267222.4 → NP_001254151.1  HIG1 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254151.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q21524
    Conserved Domains (1) summary
    pfam04588
    Location:78 → 128
    HIG_1_N; Hypoxia induced protein conserved region

  2. NM_001381527.1 → NP_001367209.1  HIG1 domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7WN91
    Conserved Domains (1) summary
    pfam04588
    Location:71 → 120
    HIG_1_N; Hypoxia induced protein conserved region
Nucleotide Protein
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