nhr-21 NR LBD domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: nhr-21
Official Full Name: NR LBD domain-containing protein
Primary source: WormBase:WBGene00003620
Locus tag: CELE_F21D12.1
See related: AllianceGenome:WB:WBGene00003620
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in spermatheca. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See nhr-21 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 10

Sequence:: Chromosome: II; NC_003280.10 (7339229..7349133)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F21D12.1 (e-PCR)
- UniSTS:317478

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: NR LBD domain-containing protein

NP_001022100.1

Confirmed by transcript evidence

NP_001022101.1

Partially confirmed by transcript evidence

NP_001022102.1

Confirmed by transcript evidence

NP_001022103.1

Confirmed by transcript evidence

NP_001040766.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

7339229..7349133

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001026931.7 → NP_001022102.1 NR LBD domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001022102.1

Status: REVIEWED

UniProtKB/TrEMBL

H2KZU2, Q9UAN6

Conserved Domains (2) summary

cd06157
Location:236 → 406

NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

cd06960
Location:22 → 97

NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
NM_001047301.4 → NP_001040766.1 NR LBD domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001040766.1

Status: REVIEWED

UniProtKB/TrEMBL

H2KZU4, Q9UAN6

Conserved Domains (2) summary

cd06157
Location:244 → 416

NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

cd06960
Location:30 → 105

NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
NM_001026929.5 → NP_001022100.1 NR LBD domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001022100.1

Status: REVIEWED

UniProtKB/TrEMBL

H2KZU1, Q9UAN6

Conserved Domains (2) summary

cd06157
Location:242 → 414

NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

cd06960
Location:30 → 105

NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
NM_001026932.5 → NP_001022103.1 NR LBD domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001022103.1

Status: REVIEWED

UniProtKB/TrEMBL

H2KZU3, Q9UAN6

Conserved Domains (2) summary

cd06157
Location:242 → 412

NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

cd06960
Location:30 → 105

NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
NM_001026930.4 → NP_001022101.1 NR LBD domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001022101.1

Status: REVIEWED

UniProtKB/TrEMBL

G5EBL9, Q9UAN6

Conserved Domains (2) summary

cd06157
Location:196 → 366

NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

cl02596
Location:27 → 57

NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers