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C56C10.6 Protein kinase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 174087, updated on 4-Jan-2025

Summary

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Official Symbol
C56C10.6
Official Full Name
Protein kinase domain-containing protein
Primary source
WormBase:WBGene00016963
Locus tag
CELE_C56C10.6
See related
AllianceGenome:WB:WBGene00016963
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Orthologous to human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See C56C10.6 in Genome Data Viewer
Location:
chromosome: II
Exon count:
7
Sequence:
Chromosome: II; NC_003280.10 (6579683..6581336, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serpentine receptor class alpha-29 Neighboring gene Serpentine receptor class alpha-31 Neighboring gene protein of unknown function DB domain-containing protein Neighboring gene putative trafficking protein particle complex subunit 13 homolog Neighboring gene Transcription factor BTF3 homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Protein kinase domain-containing protein
NP_495333.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    6579683..6581336 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_062932.4 → NP_495333.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495333.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18882
    Conserved Domains (2) summary
    pfam11600
    Location:322 → 407
    CAF-1_p150; Chromatin assembly factor 1 complex p150 subunit, N-terminal
    cl21453
    Location:24 → 290
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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