U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

rgs-3 RGS domain-containing protein;Regulator of G-protein signaling rgs-3 [ Caenorhabditis elegans ]

Gene ID: 174020, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
rgs-3
Official Full Name
RGS domain-containing protein;Regulator of G-protein signaling rgs-3
Primary source
WormBase:WBGene00004346
Locus tag
CELE_C29H12.3
See related
AllianceGenome:WB:WBGene00004346
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in chemosensory behavior and sensory perception of bitter taste. Is expressed in amphid neurons and phasmid neurons. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See rgs-3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
8
Sequence:
Chromosome: II; NC_003280.10 (6099800..6110126)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene DUF19 domain-containing protein Neighboring gene Tripeptidyl-peptidase 2 Neighboring gene Retinoblastoma-binding protein homolog 5 Neighboring gene ncRNA Neighboring gene Chromo domain-containing protein Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Inhibition of the expression of rgs-3 alleviates propofol-induced decline in learning and memory in Caenorhabditis elegans. Zhao A, et al. CNS Neurosci Ther, 2023 Jan. PMID 36284438, Free PMC Article
  2. Navigational choice between reversal and curve during acidic pH avoidance behavior in Caenorhabditis elegans. Wakabayashi T, et al. BMC Neurosci, 2015 Nov 19. PMID 26584677, Free PMC Article
  3. The C. elegans D2-like dopamine receptor DOP-3 decreases behavioral sensitivity to the olfactory stimulus 1-octanol. Ezak MJ, et al. PLoS One, 2010 Mar 2. PMID 20209143, Free PMC Article
  4. The C. elegans cGMP-dependent protein kinase EGL-4 regulates nociceptive behavioral sensitivity. Krzyzanowski MC, et al. PLoS Genet, 2013. PMID 23874221, Free PMC Article
  5. C. elegans G protein regulator RGS-3 controls sensitivity to sensory stimuli. Ferkey DM, et al. Neuron, 2007 Jan 4. PMID 17196529, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in chemosensory behavior IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in chemosensory behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of bitter taste IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in sensory perception of bitter taste IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
RGS domain-containing protein;Regulator of G-protein signaling rgs-3
NP_001379742.1
  • Confirmed by transcript evidence
NP_495223.1
  • Confirmed by transcript evidence
NP_871896.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    6099800..6110126
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_062822.4 → NP_495223.1  Regulator of G-protein signaling rgs-3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495223.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q18312
    Conserved Domains (2) summary
    smart00315
    Location:112 → 218
    RGS; Regulator of G protein signalling domain
    pfam00615
    Location:240 → 358
    RGS; Regulator of G protein signaling domain

  2. NM_182096.6 → NP_871896.1  RGS domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_871896.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MQB2
    Conserved Domains (2) summary
    smart00315
    Location:39 → 145
    RGS; Regulator of G protein signalling domain
    pfam00615
    Location:167 → 285
    RGS; Regulator of G protein signaling domain

  3. NM_001393090.1 → NP_001379742.1  RGS domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5DX43
    Conserved Domains (2) summary
    smart00315
    Location:33 → 139
    RGS; Regulator of G protein signalling domain
    pfam00615
    Location:161 → 279
    RGS; Regulator of G protein signaling domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q18312.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.