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sec-6 Exocyst complex component 3 [ Caenorhabditis elegans ]

Gene ID: 173910, updated on 2-Nov-2024

Summary

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Official Symbol
sec-6
Official Full Name
Exocyst complex component 3
Primary source
WormBase:WBGene00017284
Locus tag
CELE_F09E5.5
See related
AllianceGenome:WB:WBGene00017284
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization and exocytosis. Predicted to be part of exocyst. Is expressed in intestine; muscle cell; and nervous system. Orthologous to several human genes including EXOC3 (exocyst complex component 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sec-6 in Genome Data Viewer
Location:
chromosome: II
Exon count:
14
Sequence:
Chromosome: II; NC_003280.10 (5359552..5372182)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Boca/MESD chaperone for YWTD beta-propeller-EGF Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U-scoloptoxin(04)- Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene AlkylGuanine DNA alkylTransferase Neighboring gene Putative deoxyribose-phosphate aldolase Neighboring gene Alpha-1,3/1,6-mannosyltransferase ALG2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nucleolin regulates 14-3-3ζ mRNA and promotes cofilin phosphorylation to induce tunneling nanotube formation. Dagar S, et al. FASEB J, 2021 Jan. PMID 33222276
  2. Polarized exocyst-mediated vesicle fusion directs intracellular lumenogenesis within the C. elegans excretory cell. Armenti ST, et al. Dev Biol, 2014 Oct 1. PMID 25102190, Free PMC Article
  3. RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans. Frische EW, et al. EMBO J, 2007 Dec 12. PMID 17989692, Free PMC Article
  4. The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans. Brinzer RA, et al. G3 (Bethesda), 2024 Mar 6. PMID 38227795, Free PMC Article
  5. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in exocyst localization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in exocytosis IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of exocyst IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of exocyst IEA
Inferred from Electronic Annotation
more info
  
part_of exocyst ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
Exocyst complex component 3
NP_495006.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    5359552..5372182
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_062605.9 → NP_495006.2  Exocyst complex component 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495006.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q19262
    Conserved Domains (1) summary
    cl19885
    Location:179 → 747
    Sec6; Exocyst complex component Sec6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q19262.2

Gene LinkOut

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