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bmy-1 Boca/MESD chaperone for YWTD beta-propeller-EGF [ Caenorhabditis elegans ]

Gene ID: 173908, updated on 4-Jan-2025

Summary

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Official Symbol
bmy-1
Official Full Name
Boca/MESD chaperone for YWTD beta-propeller-EGF
Primary source
WormBase:WBGene00017293
Locus tag
CELE_F09E5.17
See related
AllianceGenome:WB:WBGene00017293
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables identical protein binding activity. Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 20. Orthologous to human MESD (mesoderm development LRP chaperone). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See bmy-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (5358695..5359469)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serpentine receptor class gamma-69 Neighboring gene Transmembrane protein 199 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Exocyst complex component 3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U-scoloptoxin(04)-

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural characterization of the Boca/Mesd maturation factors for LDL-receptor-type β propeller domains. Collins MN, et al. Structure, 2011 Mar 9. PMID 21397184, Free PMC Article
  2. Ca(2+)/Calmodulin-binding proteins from the C. elegans proteome. Shen X, et al. Cell Calcium, 2008 May. PMID 17854888
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Boca/MESD chaperone for YWTD beta-propeller-EGF
NP_495003.2
  • Product from WormBase gene class bmy;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    5358695..5359469
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_062602.3 → NP_495003.2  Boca/MESD chaperone for YWTD beta-propeller-EGF [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495003.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IG33
    Conserved Domains (1) summary
    pfam10185
    Location:24 → 186
    Mesd; Chaperone for wingless signalling and trafficking of LDL receptor
Nucleotide Protein
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