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col-40 Cuticle collagen 40 [ Caenorhabditis elegans ]

Gene ID: 173495, updated on 4-Jan-2025

Summary

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Official Symbol
col-40
Official Full Name
Cuticle collagen 40
Primary source
WormBase:WBGene00000617
Locus tag
CELE_T13B5.4
See related
AllianceGenome:WB:WBGene00000617
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. Is expressed in hypodermis. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See col-40 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003280.10 (1104942..1106964, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Leishmanolysin-like peptidase Neighboring gene tRNA Neighboring gene tRNA-Thr Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene LIPaSe related Neighboring gene LIPaSe related

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification, sequence and expression patterns of the Caenorhabditis elegans col-36 and col-40 collagen-encoding genes. Levy AD, et al. Gene, 1993 Dec 31. PMID 8299960
  2. The effects of different biochars on Caenorhabditis elegans and the underlying transcriptomic mechanisms. Chen Y, et al. PLoS One, 2023. PMID 37738276, Free PMC Article
  3. Genetic markers enable the verification and manipulation of the dauer entry decision. Shih PY, et al. Dev Biol, 2019 Oct 15. PMID 31242447
  4. The cuticle of the nematode Caenorhabditis elegans: a complex collagen structure. Johnstone IL. Bioessays, 1994 Mar. PMID 8166670
  5. Analysis of mutations in the sqt-1 and rol-6 collagen genes of Caenorhabditis elegans. Kramer JM, et al. Genetics, 1993 Dec. PMID 8307321, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables structural constituent of cuticle IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of cuticle NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in collagen and cuticulin-based cuticle development NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
Cuticle collagen 40
NP_493913.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    1104942..1106964 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_061512.5 → NP_493913.2  Cuticle collagen 40 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493913.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O17374, P34804
    Conserved Domains (2) summary
    pfam01391
    Location:253 → 285
    Collagen; Collagen triple helix repeat (20 copies)
    smart01088
    Location:15 → 66
    Col_cuticle_N; Nematode cuticle collagen N-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34804.3

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