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far-7 Fatty Acid/Retinol binding protein [ Caenorhabditis elegans ]

Gene ID: 173421, updated on 9-Dec-2024

Summary

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Official Symbol
far-7
Official Full Name
Fatty Acid/Retinol binding protein
Primary source
WormBase:WBGene00001391
Locus tag
CELE_K01A2.2
See related
AllianceGenome:WB:WBGene00001391
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables oleic acid binding activity. Located in cytoplasm. Is expressed in excretory cell; hypodermis; and in male. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See far-7 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (319789..321110)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene MiRP K channel accessory Subunit Neighboring gene MiRP K channel accessory Subunit Neighboring gene ncRNA Neighboring gene CCDC92 domain-containing protein;CCDC92/74 N-terminal domain-containing protein Neighboring gene Beta-sarcoglycan

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Diversity in the structures and ligand-binding sites of nematode fatty acid and retinol-binding proteins revealed by Na-FAR-1 from Necator americanus. Rey-Burusco MF, et al. Biochem J, 2015 Nov 1. PMID 26318523, Free PMC Article
  2. Fatty acid- and retinoid-binding proteins have distinct binding pockets for the two types of cargo. Jordanova R, et al. J Biol Chem, 2009 Dec 18. PMID 19828452, Free PMC Article
  3. The FAR protein family of the nematode Caenorhabditis elegans. Differential lipid binding properties, structural characteristics, and developmental regulation. Garofalo A, et al. J Biol Chem, 2003 Mar 7. PMID 12502713
  4. PQM-1 controls hypoxic survival via regulation of lipid metabolism. Heimbucher T, et al. Nat Commun, 2020 Oct 2. PMID 33009389, Free PMC Article
  5. A Mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and -independent pathways in C. elegans. Taubert S, et al. Genes Dev, 2006 May 1. PMID 16651656, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
enables oleic acid binding IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Fatty Acid/Retinol binding protein
NP_001300557.1
  • Product from WormBase gene class far;
    Confirmed by transcript evidence
NP_493708.1
  • Product from WormBase gene class far;
    Confirmed by transcript evidence
NP_871991.2
  • Product from WormBase gene class far;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    319789..321110
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_061307.8 → NP_493708.1  Fatty Acid/Retinol binding protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493708.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9TZ51
    Conserved Domains (1) summary
    pfam05823
    Location:11 → 136
    Gp-FAR-1; Nematode fatty acid retinoid binding protein (Gp-FAR-1)

  2. NM_182191.6 → NP_871991.2  Fatty Acid/Retinol binding protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KY95
    Conserved Domains (1) summary
    pfam05823
    Location:1 → 88
    Gp-FAR-1; Nematode fatty acid retinoid binding protein (Gp-FAR-1)

  3. NM_001313628.3 → NP_001300557.1  Fatty Acid/Retinol binding protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3AWY0

RNA

  1. NR_132574.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

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