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F22G12.5 DOCKER domain-containing protein;PH domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 173181, updated on 4-Jan-2025

Summary

Official Symbol
F22G12.5
Official Full Name
DOCKER domain-containing protein;PH domain-containing protein
Primary source
WormBase:WBGene00009065
Locus tag
CELE_F22G12.5
See related
AllianceGenome:WB:WBGene00009065
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of Rho protein signal transduction. Is expressed in intestine; nervous system; spermatheca; and uterine toroidal epithelial cell. Orthologous to several human genes including DOCK11 (dedicator of cytokinesis 11). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See F22G12.5 in Genome Data Viewer
Location:
chromosome: I
Exon count:
29
Sequence:
Chromosome: I; NC_003279.8 (13162492..13182726)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ANK_REP_REGION domain-containing protein;FYVE-type domain-containing protein Neighboring gene tRNA-Val Neighboring gene ncRNA Neighboring gene tRNA-Val Neighboring gene Defensin-like protein Neighboring gene protein-disulfide reductase

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
DOCKER domain-containing protein;PH domain-containing protein
NP_001252088.2
  • Confirmed by transcript evidence
NP_001252089.1
  • Confirmed by transcript evidence
NP_001300393.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    13162492..13182726
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001265159.4NP_001252088.2  PH domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001252088.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EBE8
    Conserved Domains (4) summary
    pfam06920
    Location:18032301
    DHR-2; Dock homology region 2
    pfam11878
    Location:79189
    DUF3398; Domain of unknown function (DUF3398)
    cl14603
    Location:758945
    C2; C2 domain
    cl17171
    Location:208326
    PH-like; Pleckstrin homology-like domain
  2. NM_001313464.2NP_001300393.1  PH domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3AR51
    Conserved Domains (4) summary
    pfam06920
    Location:18052303
    DHR-2; Dock homology region 2
    pfam11878
    Location:79189
    DUF3398; Domain of unknown function (DUF3398)
    cl14603
    Location:760947
    C2; C2 domain
    cl17171
    Location:208326
    PH-like; Pleckstrin homology-like domain
  3. NM_001265160.3NP_001252089.1  DOCKER domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001252089.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G1K0Y1
    Conserved Domains (1) summary
    pfam06920
    Location:7341232
    DHR-2; Dock homology region 2