F16A11.1 RING finger and SPRY domain-containing protein 1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: F16A11.1
Official Full Name: RING finger and SPRY domain-containing protein 1
Primary source: WormBase:WBGene00008876
Locus tag: CELE_F16A11.1
See related: AllianceGenome:WB:WBGene00008876
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be active in cytoplasm. Is expressed in body wall musculature; hypodermis; nervous system; and reproductive system. Orthologous to human RSPRY1 (ring finger and SPRY domain containing 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See F16A11.1 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 9

Sequence:: Chromosome: I; NC_003279.8 (9393761..9404039, complement)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F16A11.1 (e-PCR)
- UniSTS:307492

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables ubiquitin-protein transferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin-protein transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in proteolysis involved in protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: RING finger and SPRY domain-containing protein 1

NP_001129765.1

Confirmed by transcript evidence

NP_492499.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

9393761..9404039 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_060098.6 → NP_492499.1 RING finger and SPRY domain-containing protein 1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492499.1

Status: REVIEWED

UniProtKB/TrEMBL

P90839

Conserved Domains (2) summary

pfam13920
Location:561 → 605

zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)

cd12883
Location:393 → 516

SPRY_RING; SPRY domain at N-terminus of Really Interesting New Gene (RING) finger domain
NM_001136293.3 → NP_001129765.1 RING finger and SPRY domain-containing protein 1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001129765.1

Status: REVIEWED

UniProtKB/TrEMBL

B3WFX6

Conserved Domains (2) summary

pfam13920
Location:509 → 553

zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)

cd12883
Location:341 → 464

SPRY_RING; SPRY domain at N-terminus of Really Interesting New Gene (RING) finger domain