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ZK858.6 Transmembrane 9 superfamily member [ Caenorhabditis elegans ]

Gene ID: 172739, updated on 4-Jan-2025

Summary

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Official Symbol
ZK858.6
Official Full Name
Transmembrane 9 superfamily member
Primary source
WormBase:WBGene00014119
Locus tag
CELE_ZK858.6
See related
AllianceGenome:WB:WBGene00014119
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in protein localization to membrane. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Predicted to be active in membrane. Is expressed in intestine. Orthologous to human TM9SF4 (transmembrane 9 superfamily member 4). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ZK858.6 in Genome Data Viewer
Location:
chromosome: I
Exon count:
11
Sequence:
Chromosome: I; NC_003279.8 (9138406..9145632, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein maternal effect lethal 26;Protein roadkill Neighboring gene TM2 domain-containing protein ZK858.5 Neighboring gene ncRNA Neighboring gene tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 Neighboring gene Amino acid transporter transmembrane domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in intracellular monoatomic cation homeostasis IEA
Inferred from Electronic Annotation
more info
  
involved_in protein localization to membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Transmembrane 9 superfamily member
NP_001129804.1
  • Partially confirmed by transcript evidence
NP_001367071.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    9138406..9145632 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001136332.3 → NP_001129804.1  Transmembrane 9 superfamily member [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001129804.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3WFW5
    Conserved Domains (1) summary
    pfam02990
    Location:90 → 613
    EMP70; Endomembrane protein 70

  2. NM_001380961.1 → NP_001367071.1  Transmembrane 9 superfamily member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YTF9
    Conserved Domains (1) summary
    pfam02990
    Location:53 → 576
    EMP70; Endomembrane protein 70
Nucleotide Protein
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