U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

egg-6 Leucine-rich repeat-containing protein egg-6 [ Caenorhabditis elegans ]

Gene ID: 172670, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
egg-6
Official Full Name
Leucine-rich repeat-containing protein egg-6
Primary source
WormBase:WBGene00010621
Locus tag
CELE_K07A12.2
See related
AllianceGenome:WB:WBGene00010621
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in cell development. Predicted to be located in apical plasma membrane. Is expressed in hypodermis; interfacial epithelial cell; neurons; pharynx; and vulva. [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See egg-6 in Genome Data Viewer
Location:
chromosome: I
Exon count:
9
Sequence:
Chromosome: I; NC_003279.8 (8676666..8681325, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Nulp1-pending protein Neighboring gene Ovule protein Neighboring gene ncRNA Neighboring gene Homolog of Odr-2 (Two) Neighboring gene Tr-type G domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Extracellular leucine-rich repeat proteins are required to organize the apical extracellular matrix and maintain epithelial junction integrity in C. elegans. Mancuso VP, et al. Development, 2012 Mar. PMID 22278925, Free PMC Article
  2. Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos. Quarato P, et al. Nat Commun, 2021 Mar 4. PMID 33664268, Free PMC Article
  3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in cell development IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Leucine-rich repeat-containing protein egg-6
NP_492348.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    8676666..8681325 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059947.6 → NP_492348.1  Leucine-rich repeat-containing protein egg-6 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492348.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P90920
    Conserved Domains (4) summary
    cd00116
    Location:240 → 458
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:437 → 449
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:201 → 224
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:365 → 425
    LRR_8; Leucine rich repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P90920.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools