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flp-22 SPSAKWMRF-amide 3 [ Caenorhabditis elegans ]

Gene ID: 172665, updated on 4-Jan-2025

Summary

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Official Symbol
flp-22
Official Full Name
SPSAKWMRF-amide 3
Primary source
WormBase:WBGene00009562
Locus tag
CELE_F39H2.1
See related
AllianceGenome:WB:WBGene00009562
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables neuropeptide receptor binding activity. Involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Is expressed in neurons and uv1. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See flp-22 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003279.8 (8658899..8659967)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene t-SNARE coiled-coil homology domain-containing protein Neighboring gene Peptidyl-prolyl cis-trans isomerase sig-7 Neighboring gene 5' exonuclease Apollo Neighboring gene Synaptonemal complex protein 3 Neighboring gene Aminomethyltransferase folate-binding domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. FMRFamide-related neuropeptide gene family in Caenorhabditis elegans. Li C, et al. Brain Res, 1999 Nov 27. PMID 10612695
  2. FMRFamide related peptide ligands activate the Caenorhabditis elegans orphan GPCR Y59H11AL.1. Mertens I, et al. Peptides, 2006 Jun. PMID 16377032
  3. Presynaptic coupling by electrical synapses coordinates a rhythmic behavior by synchronizing the activities of a neuron pair. Choi U, et al. Proc Natl Acad Sci U S A, 2021 May 18. PMID 33972428, Free PMC Article
  4. The ovijector of Ascaris suum: multiple response types revealed by Caenorhabditis elegans FMRFamide-related peptides. Moffett CL, et al. Int J Parasitol, 2003 Jul 30. PMID 12865086
  5. Peptidomics of Caenorhabditis elegans: in search of neuropeptides. Husson SJ, et al. Commun Agric Appl Biol Sci, 2005. PMID 16366296

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables neuropeptide receptor binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in neuropeptide signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
SPSAKWMRF-amide 3
NP_492344.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    8658899..8659967
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059943.8 → NP_492344.2  SPSAKWMRF-amide 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492344.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q93702
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q93702.2

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