mog-7 GCF C-terminal domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: mog-7
Official Full Name: GCF C-terminal domain-containing protein
Primary source: WormBase:WBGene00009672
Locus tag: CELE_F43G9.12
See related: AllianceGenome:WB:WBGene00009672
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable DNA binding activity. Predicted to be involved in spliceosomal complex disassembly. Predicted to be part of U2-type post-mRNA release spliceosomal complex. Predicted to be active in nucleus. Is expressed in germ cell; germline precursor cell; and somatic cell. Orthologous to human GCFC2 (GC-rich sequence DNA-binding factor 2) and PAXBP1 (PAX3 and PAX7 binding protein 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See mog-7 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 10

Sequence:: Chromosome: I; NC_003279.8 (8640508..8644399)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F43G9.12 (e-PCR)
- UniSTS:307643

F43G9.10 (e-PCR)
- UniSTS:321469

STS1-158 (e-PCR)
- UniSTS:241645

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
involved_in spliceosomal complex disassembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of U2-type post-mRNA release spliceosomal complex	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: GCF C-terminal domain-containing protein

NP_001250839.1

Confirmed by transcript evidence

NP_001250840.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

8640508..8644399

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001263910.2 → NP_001250839.1 GCF C-terminal domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001250839.1

Status: REVIEWED

UniProtKB/TrEMBL

G5ECH1

Conserved Domains (1) summary

pfam07842
Location:537 → 671

GCFC; GC-rich sequence DNA-binding factor-like protein
NM_001263911.3 → NP_001250840.1 GCF C-terminal domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001250840.1

Status: REVIEWED

UniProtKB/TrEMBL

G5EBK6

Conserved Domains (1) summary

pfam07842
Location:37 → 171

GCFC; GC-rich sequence DNA-binding factor-like protein