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F26A3.4 Protein-tyrosine-phosphatase [ Caenorhabditis elegans ]

Gene ID: 172525, updated on 4-Jan-2025

Summary

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Official Symbol
F26A3.4
Official Full Name
Protein-tyrosine-phosphatase
Primary source
WormBase:WBGene00009142
Locus tag
CELE_F26A3.4
See related
AllianceGenome:WB:WBGene00009142
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable phosphoprotein phosphatase activity. Predicted to be involved in protein dephosphorylation. Located in striated muscle dense body. Is expressed in neurons. Orthologous to human DUSP28 (dual specificity phosphatase 28). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See F26A3.4 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (7656978..7658291, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene RNA-directed RNA polymerase Neighboring gene ncRNA Neighboring gene DDE_Tnp_1_7 domain-containing protein Neighboring gene DEgenerin Like Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in striated muscle dense body HDA PubMed 

General protein information

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Preferred Names
Protein-tyrosine-phosphatase
NP_492133.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    7656978..7658291 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059732.5 → NP_492133.1  Protein-tyrosine-phosphatase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492133.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q93592
    Conserved Domains (1) summary
    cd00127
    Location:14 → 149
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
Nucleotide Protein
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