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dpy-14 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172410, updated on 4-Jan-2025

Summary

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Official Symbol
dpy-14
Official Full Name
Nematode cuticle collagen N-terminal domain-containing protein
Primary source
WormBase:WBGene00001075
Locus tag
CELE_H27M09.4
See related
AllianceGenome:WB:WBGene00001075
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Is expressed in anterior ganglion; hypodermis; and lateral ganglion left neurons. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See dpy-14 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (6843589..6845142)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Adenosylhomocysteinase Neighboring gene Dipeptidyl Peptidase Four (IV) family Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Caenorhabditis elegans dpy-14: an essential collagen gene with unique expression profile and physiological roles in early development. Gallo M, et al. Mol Genet Genomics, 2006 Jun. PMID 16496175
  2. Somatic excision of transposable element Tc1 from the Bristol genome of Caenorhabditis elegans. Harris LJ, et al. Mol Cell Biol, 1986 May. PMID 3023903, Free PMC Article
  3. Toxic Effects of Size-tunable Gold Nanoparticles on Caenorhabditis elegans Development and Gene Regulation. Hu CC, et al. Sci Rep, 2018 Oct 15. PMID 30323250, Free PMC Article
  4. Molecular characterization in the dpy-14 region identifies the adenosylhomocysteine hydrolase gene in Caenorhabditis elegans. Prasad SS, et al. Genome, 1993 Feb. PMID 8458573
  5. The effect of gamma radiation on recombination frequency in Caenorhabditis elegans. Kim JS, et al. Genome, 1987 Jun. PMID 3609740

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables structural constituent of cuticle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nematode cuticle collagen N-terminal domain-containing protein
NP_491958.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    6843589..6845142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059557.7 → NP_491958.1  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491958.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EEB6
    Conserved Domains (2) summary
    pfam01391
    Location:180 → 223
    Collagen; Collagen triple helix repeat (20 copies)
    smart01088
    Location:20 → 64
    Col_cuticle_N; Nematode cuticle collagen N-terminal domain
Nucleotide Protein
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