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tre-1 Trehalase [ Caenorhabditis elegans ]

Gene ID: 172371, updated on 4-Jan-2025

Summary

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Official Symbol
tre-1
Official Full Name
Trehalase
Primary source
WormBase:WBGene00006607
Locus tag
CELE_F57B10.7
See related
AllianceGenome:WB:WBGene00006607
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable alpha,alpha-trehalase activity. Predicted to be involved in trehalose catabolic process. Orthologous to human TREH (trehalase). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See tre-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
9
Sequence:
Chromosome: I; NC_003279.8 (6554729..6558665)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1 Neighboring gene ncRNA Neighboring gene XPG (Xeroderma Pigmentosum group G) DNA repair gene homolog Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Disruption of O-GlcNAc Cycling in C. elegans Perturbs Nucleotide Sugar Pools and Complex Glycans. Ghosh SK, et al. Front Endocrinol (Lausanne), 2014. PMID 25505447, Free PMC Article
  2. Trehalose metabolism genes in Caenorhabditis elegans and filarial nematodes. Pellerone FI, et al. Int J Parasitol, 2003 Sep 30. PMID 13678635
  3. Genetic and biochemical analysis of TGF beta signal transduction. Padgett RW, et al. Cytokine Growth Factor Rev, 1997 Mar. PMID 9174659
  4. An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans. Meissner B, et al. PLoS Genet, 2009 Jun. PMID 19557190, Free PMC Article
  5. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables alpha,alpha-trehalase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alpha,alpha-trehalase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in trehalose catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in trehalose metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Trehalase
NP_491890.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    6554729..6558665
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059489.7 → NP_491890.2  Trehalase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491890.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EC40
    Conserved Domains (2) summary
    COG1626
    Location:9 → 542
    TreA; Neutral trehalase [Carbohydrate transport and metabolism]
    cl17346
    Location:28 → 536
    Trehalase; Trehalase
Nucleotide Protein
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