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cey-2 CSD domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172219, updated on 2-Nov-2024

Summary

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Official Symbol
cey-2
Official Full Name
CSD domain-containing protein
Primary source
WormBase:WBGene00000473
Locus tag
CELE_F46F11.2
See related
AllianceGenome:WB:WBGene00000473
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable nucleic acid binding activity. Predicted to be involved in regulation of gene expression. Part of ribonucleoprotein complex. Is expressed in germ cell; germ line; pharynx; and somatic cell. Used to study Huntington's disease and neurodegenerative disease. Orthologous to human YBX2 (Y-box binding protein 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cey-2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003279.8 (5619569..5620669)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Trafficking protein particle complex subunit 8 Neighboring gene ncRNA Neighboring gene F-box domain-containing protein Neighboring gene Tenascin Neighboring gene RNA (guanine-9-)-methyltransferase domain-containing protein 1 Neighboring gene C2H2-type domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. cdk-7 Is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos. Wallenfang MR, et al. Proc Natl Acad Sci U S A, 2002 Apr 16. PMID 11960010, Free PMC Article
  2. A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans. Audhya A, et al. J Cell Biol, 2005 Oct 24. PMID 16247027, Free PMC Article
  3. GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development. Jones AR, et al. Dev Biol, 1996 Nov 25. PMID 8948583
  4. Genome-wide analysis of GLD-1-mediated mRNA regulation suggests a role in mRNA storage. Scheckel C, et al. PLoS Genet, 2012 May. PMID 22693456, Free PMC Article
  5. RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans. Montgomery MK, et al. Proc Natl Acad Sci U S A, 1998 Dec 22. PMID 9860998, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables nucleic acid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
CSD domain-containing protein
NP_491645.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    5619569..5620669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059244.7 → NP_491645.1  CSD domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491645.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    P91306
    Conserved Domains (1) summary
    pfam00313
    Location:66 → 136
    CSD; 'Cold-shock' DNA-binding domain
Nucleotide Protein
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