U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

chp-1 Cysteine and histidine-rich domain-containing protein 1 [ Caenorhabditis elegans ]

Gene ID: 172138, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
chp-1
Official Full Name
Cysteine and histidine-rich domain-containing protein 1
Primary source
WormBase:WBGene00000502
Locus tag
CELE_Y110A7A.13
See related
AllianceGenome:WB:WBGene00000502
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable zinc ion binding activity. Predicted to be involved in centrosome duplication. Orthologous to human CHORDC1 (cysteine and histidine rich domain containing 1) and ITGB1BP2 (integrin subunit beta 1 binding protein 2). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See chp-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (5103581..5104911, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene Intraflagellar transport protein 20 homolog Neighboring gene V-type proton ATPase subunit B 2 Neighboring gene ncRNA Neighboring gene Proteasome subunit alpha type-4

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The CHORD protein CHP-1 regulates EGF receptor trafficking and signaling in C. elegans and in human cells. Haag A, et al. Elife, 2020 Feb 13. PMID 32053105, Free PMC Article
  2. A novel class of eukaryotic zinc-binding proteins is required for disease resistance signaling in barley and development in C. elegans. Shirasu K, et al. Cell, 1999 Nov 12. PMID 10571178
  3. Efficient target-selected mutagenesis in Caenorhabditis elegans: toward a knockout for every gene. Cuppen E, et al. Genome Res, 2007 May. PMID 17416746, Free PMC Article
  4. An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans. Meissner B, et al. PLoS Genet, 2009 Jun. PMID 19557190, Free PMC Article
  5. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in centrosome duplication IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Cysteine and histidine-rich domain-containing protein 1
NP_491519.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    5103581..5104911 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059118.7 → NP_491519.1  Cysteine and histidine-rich domain-containing protein 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491519.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EEI8
    Conserved Domains (2) summary
    cd06466
    Location:224 → 307
    p23_CS_SGT1_like; p23_like domain similar to the C-terminal CHORD-SGT1 (CS) domain of Sgt1 (suppressor of G2 allele of Skp1). Sgt1 interacts with multiple protein complexes and has the features of a cochaperone. Human (h) Sgt1 interacts with both Hsp70 and Hsp90, and has ...
    pfam04968
    Location:7 → 68
    CHORD
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
G5EEI8.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools