U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

tmem-39 uncharacterized protein [ Caenorhabditis elegans ]

Gene ID: 172060, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
tmem-39
Official Full Name
uncharacterized protein
Primary source
WormBase:WBGene00017003
Locus tag
CELE_D1007.5
See related
AllianceGenome:WB:WBGene00017003
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be active in membrane. Is expressed in hypodermis; intestine; and nervous system. Orthologous to human TMEM39A (transmembrane protein 39A) and TMEM39B (transmembrane protein 39B). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See tmem-39 in Genome Data Viewer
Location:
chromosome: I
Exon count:
6
Sequence:
Chromosome: I; NC_003279.8 (4580708..4583810, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Secreted protein Neighboring gene AD domain-containing protein Neighboring gene Plectin/eS10 N-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The conserved autoimmune-disease risk gene TMEM39A regulates lysosome dynamics. Luo S, et al. Proc Natl Acad Sci U S A, 2021 Feb 9. PMID 33531362, Free PMC Article
  2. Acquired stress resilience through bacteria-to-nematode interdomain horizontal gene transfer. Pandey T, et al. EMBO J, 2023 Dec 11. PMID 37953666, Free PMC Article
  3. The conserved transmembrane protein TMEM-39 coordinates with COPII to promote collagen secretion and regulate ER stress response. Zhang Z, et al. PLoS Genet, 2021 Feb. PMID 33524011, Free PMC Article
  4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
NP_001021071.1
  • Partially confirmed by transcript evidence;
    Product from WormBase gene class tmem; TMEM (human TransMEMbrane protein) homolog
NP_001021072.1
  • Partially confirmed by transcript evidence;
    Product from WormBase gene class tmem; TMEM (human TransMEMbrane protein) homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    4580708..4583810 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001025900.5 → NP_001021071.1  uncharacterized protein CELE_D1007.5 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021071.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O01870
    Conserved Domains (1) summary
    pfam10271
    Location:17 → 461
    Tmp39; Putative transmembrane protein

  2. NM_001025901.6 → NP_001021072.1  uncharacterized protein CELE_D1007.5 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021072.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZB3
    Conserved Domains (1) summary
    pfam10271
    Location:17 → 395
    Tmp39; Putative transmembrane protein
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools