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zip-4 Transcription factor zip-4 [ Caenorhabditis elegans ]

Gene ID: 171900, updated on 9-Dec-2024

Summary

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Official Symbol
zip-4
Official Full Name
Transcription factor zip-4
Primary source
WormBase:WBGene00021552
Locus tag
CELE_Y44E3B.1
See related
AllianceGenome:WB:WBGene00021552
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to Gram-negative bacterium. Predicted to be located in nucleus. Is expressed in gonad; pharynx; and vulva. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See zip-4 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (3264111..3266762, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Tyrosinase copper-binding domain-containing protein Neighboring gene Nop domain-containing protein Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A conserved mitochondrial surveillance pathway is required for defense against Pseudomonas aeruginosa. Tjahjono E, et al. PLoS Genet, 2017 Jun. PMID 28662060, Free PMC Article
  2. Networks of bZIP protein-protein interactions diversified over a billion years of evolution. Reinke AW, et al. Science, 2013 May 10. PMID 23661758, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to Gram-negative bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Transcription factor zip-4
NP_001040703.1
  • Confirmed by transcript evidence
NP_001368002.1
  • Confirmed by transcript evidence
NP_491133.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    3264111..3266762 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001381600.2 → NP_001368002.1  Transcription factor zip-4 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G4SR45, H2L0N3, Q965I4
    Conserved Domains (2) summary
    cd14686
    Location:231 → 294
    bZIP; coiled coil [structural motif]
    cl21462
    Location:231 → 294
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

  2. NM_058732.5 → NP_491133.1  Transcription factor zip-4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491133.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q965I4
    Conserved Domains (2) summary
    cd14686
    Location:231 → 294
    bZIP; coiled coil [structural motif]
    cl21462
    Location:231 → 294
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

  3. NM_001047238.7 → NP_001040703.1  Transcription factor zip-4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040703.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G4SR45
    Conserved Domains (2) summary
    cd14686
    Location:168 → 231
    bZIP; coiled coil [structural motif]
    cl21462
    Location:168 → 231
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
H2L0N3.1

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