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Y71F9B.2 Phosphatidate cytidylyltransferase, mitochondrial [ Caenorhabditis elegans ]

Gene ID: 171836, updated on 4-Jan-2025

Summary

Official Symbol
Y71F9B.2
Official Full Name
Phosphatidate cytidylyltransferase, mitochondrial
Primary source
WormBase:WBGene00022126
Locus tag
CELE_Y71F9B.2
See related
AllianceGenome:WB:WBGene00022126
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable phosphatidate cytidylyltransferase activity. Predicted to be involved in CDP-diacylglycerol biosynthetic process and cardiolipin biosynthetic process. Predicted to be extrinsic component of mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 56. Orthologous to human TAMM41 (TAM41 mitochondrial translocator assembly and maintenance homolog). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See Y71F9B.2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003279.8 (2731562..2735371)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene putative small nuclear ribonucleoprotein G Neighboring gene Receptor expression-enhancing protein Neighboring gene eLRR (extracellular Leucine-Rich Repeat) ONly Neighboring gene ncRNA Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidate cytidylyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables phosphatidate cytidylyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidate cytidylyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in CDP-diacylglycerol biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in CDP-diacylglycerol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in cardiolipin biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cardiolipin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in cardiolipin biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extrinsic component of mitochondrial inner membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Phosphatidate cytidylyltransferase, mitochondrial
NP_001293366.1
  • Confirmed by transcript evidence
NP_491034.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    2731562..2735371
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058633.2NP_491034.1  Phosphatidate cytidylyltransferase, mitochondrial [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491034.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9N4G7
    Conserved Domains (1) summary
    pfam09139
    Location:4316
    Mmp37; Mitochondrial matrix Mmp37
  2. NM_001306437.3NP_001293366.1  Phosphatidate cytidylyltransferase, mitochondrial [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293366.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A078BTI5