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yop-1 Receptor expression-enhancing protein [ Caenorhabditis elegans ]

Gene ID: 171835, updated on 9-Dec-2024

Summary

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Official Symbol
yop-1
Official Full Name
Receptor expression-enhancing protein
Primary source
WormBase:WBGene00022127
Locus tag
CELE_Y71F9B.3
See related
AllianceGenome:WB:WBGene00022127
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Located in cortical endoplasmic reticulum. Is expressed in several structures, including excretory cell; nervous system; non-striated muscle; rectal gland cell; and reproductive system. Human ortholog(s) of this gene implicated in retinitis pigmentosa 77. Orthologous to human REEP5 (receptor accessory protein 5) and REEP6 (receptor accessory protein 6). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See yop-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003279.8 (2730004..2731453)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Cyclin N-terminal domain-containing protein Neighboring gene putative small nuclear ribonucleoprotein G Neighboring gene Phosphatidate cytidylyltransferase, mitochondrial Neighboring gene eLRR (extracellular Leucine-Rich Repeat) ONly Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cytoplasmic streaming drifts the polarity cue and enables posteriorization of the Caenorhabditis elegans zygote at the side opposite of sperm entry. Kimura K, et al. Mol Biol Cell, 2020 Jul 21. PMID 32459552, Free PMC Article
  2. A role for Rab5 in structuring the endoplasmic reticulum. Audhya A, et al. J Cell Biol, 2007 Jul 2. PMID 17591921, Free PMC Article
  3. A pathway for phagosome maturation during engulfment of apoptotic cells. Kinchen JM, et al. Nat Cell Biol, 2008 May. PMID 18425118, Free PMC Article
  4. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
  5. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in cortical endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
Receptor expression-enhancing protein
NP_491033.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    2730004..2731453
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058632.8 → NP_491033.1  Receptor expression-enhancing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491033.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N4G8
    Conserved Domains (1) summary
    pfam03134
    Location:60 → 147
    TB2_DP1_HVA22; TB2/DP1, HVA22 family
Nucleotide Protein
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