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C22orf42 chromosome 22 open reading frame 42 [ Homo sapiens (human) ]

Gene ID: 150297, updated on 27-Nov-2024

Summary

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Official Symbol
C22orf42provided by HGNC
Official Full Name
chromosome 22 open reading frame 42provided by HGNC
Primary source
HGNC:HGNC:27160
See related
Ensembl:ENSG00000205856 AllianceGenome:HGNC:27160
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
dJ90G24.6
Expression
Restricted expression toward testis (RPKM 3.7) See more
Orthologs
all
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Genomic context

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See C22orf42 in Genome Data Viewer
Location:
22q12.3
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (32149006..32160448, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (32613084..32624526, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (32544993..32555290, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:32519556-32520056 Neighboring gene AP1B1 pseudogene 1 Neighboring gene AP1B1 pseudogene 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:32602504-32603234 Neighboring gene SLC5A4 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:32608089-32608590 Neighboring gene ret finger protein like 2 Neighboring gene solute carrier family 5 member 4 Neighboring gene CPSF1 pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Enhanced Validation of Antibodies Enables the Discovery of Missing Proteins. Sivertsson Å, et al. J Proteome Res, 2020 Dec 4. PMID 33170010, Free PMC Article
  2. Identification of Human N-Myristoylated Proteins from Human Complementary DNA Resources by Cell-Free and Cellular Metabolic Labeling Analyses. Takamitsu E, et al. PLoS One, 2015. PMID 26308446, Free PMC Article
  3. A proteome-scale map of the SARS-CoV-2-human contactome. Kim DK, et al. Nat Biotechnol, 2023 Jan. PMID 36217029, Free PMC Article
  4. A genome annotation-driven approach to cloning the human ORFeome. Collins JE, et al. Genome Biol, 2004. PMID 15461802, Free PMC Article
  5. Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy. Sun X, et al. Acta Pharm Sin B, 2022 Feb. PMID 35256949, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
uncharacterized protein C22orf42

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001010859.3 → NP_001010859.1  uncharacterized protein C22orf42

    See identical proteins and their annotated locations for NP_001010859.1

    Status: VALIDATED

    Source sequence(s)
    AL008723, BU072847, CK818305, CR456485
    Consensus CDS
    CCDS33639.1
    UniProtKB/Swiss-Prot
    A4QPH5, Q6IC83
    Related
    ENSP00000371529.3, ENST00000382097.4

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    32149006..32160448 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017028630.3 → XP_016884119.1  uncharacterized protein C22orf42 isoform X3

  2. XM_011529922.4 → XP_011528224.1  uncharacterized protein C22orf42 isoform X1

  3. XM_017028629.3 → XP_016884118.1  uncharacterized protein C22orf42 isoform X2

  4. XM_017028631.2 → XP_016884120.1  uncharacterized protein C22orf42 isoform X4

  5. XM_017028632.3 → XP_016884121.1  uncharacterized protein C22orf42 isoform X5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    32613084..32624526 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054325145.1 → XP_054181120.1  uncharacterized protein C22orf42 isoform X6

  2. XM_054325146.1 → XP_054181121.1  uncharacterized protein C22orf42 isoform X7

  3. XM_054325148.1 → XP_054181123.1  uncharacterized protein C22orf42 isoform X2

  4. XM_054325147.1 → XP_054181122.1  uncharacterized protein C22orf42 isoform X8

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6IC83.1 GenPept UniProtKB/Swiss-Prot:Q6IC83

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