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koko kokopelli [ Drosophila melanogaster (fruit fly) ]

Gene ID: 14462485, updated on 4-Jan-2025

Summary

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Official Symbol
kokoprovided by FlyBase
Official Full Name
kokopelliprovided by FlyBase
Primary source
FLYBASE:FBgn0264816
Locus tag
Dmel_CG44010
See related
AllianceGenome:FB:FBgn0264816
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG31232; CG44010; CG7683; Dmel\CG44010
Old locus tag
Dmel_CG31232
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in syndactyly-telecanthus-anogenital and renal malformations syndrome. Orthologous to human CCNQ (cyclin Q). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See koko in Genome Data Viewer
Location:
91A6-91A6; 3-63 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18403026..18404726)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14228748..14230448)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Vacuolar H[+] ATPase 100kD subunit 2 Neighboring gene Vesicle transport through interaction with t-SNAREs 1b Neighboring gene WD repeat domain 37 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes. Palgi M, et al. BMC Genomics, 2012 Apr 11. PMID 22494833, Free PMC Article
  2. Dissecting the lean, mean, breeding machine. Nurminsky DI. Fly (Austin), 2007 Mar-Apr. PMID 19378459
  3. Photoperiod-Dependent Expression of MicroRNA in Drosophila. Pegoraro M, et al. Int J Mol Sci, 2022 Apr 29. PMID 35563325, Free PMC Article
  4. Transcriptomes of lineage-specific Drosophila neuroblasts profiled by genetic targeting and robotic sorting. Yang CP, et al. Development, 2016 Feb 1. PMID 26700685, Free PMC Article
  5. Gliogenesis in Drosophila: genome-wide analysis of downstream genes of glial cells missing in the embryonic nervous system. Egger B, et al. Development, 2002 Jul. PMID 12091301

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
kokopelli
Names
CG44010-PB
CG44010-PC
CG44010-PD
CG44010-PE
koko-PB
koko-PC
koko-PD
koko-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    18403026..18404726
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_169814.3 → NP_732341.1  kokopelli, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732341.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YU34, Q8IG98, Q9VE72
    Conserved Domains (1) summary
    pfam00134
    Location:6 → 144
    Cyclin_N; Cyclin, N-terminal domain

  2. NM_169812.3 → NP_732339.1  kokopelli, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732339.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YU34, Q8IG98, Q9VE72
    Conserved Domains (1) summary
    pfam00134
    Location:6 → 144
    Cyclin_N; Cyclin, N-terminal domain

  3. NM_169813.3 → NP_732340.1  kokopelli, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732340.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YU34, Q8IG98, Q9VE72
    Conserved Domains (1) summary
    pfam00134
    Location:6 → 144
    Cyclin_N; Cyclin, N-terminal domain

  4. NM_169811.3 → NP_732338.1  kokopelli, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732338.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YU34, Q8IG98, Q9VE72
    Conserved Domains (1) summary
    pfam00134
    Location:6 → 144
    Cyclin_N; Cyclin, N-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7YU34 Q7YU34
Q8IG98 Q8IG98
Q9VE72 Q9VE72

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials