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PH_RS07135 slipin family protein [ Pyrococcus horikoshii OT3 ]

Gene ID: 1443827, updated on 22-Oct-2024

Summary

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Gene symbol
PH_RS07135
Gene description
slipin family protein
Locus tag
PH_RS07135
Gene type
protein coding
Organism
Pyrococcus horikoshii OT3 (strain: OT3, type-material: type strain of Pyrococcus horikoshii)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus
Old locus tag
PH1511
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Genomic context

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Sequence:
NC_000961.1 (1345253..1346053)

NC_000961.1Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene NAD(P)/FAD-dependent oxidoreductase Neighboring gene nodulation protein NfeD Neighboring gene maltodextrin phosphorylase Neighboring gene [protein ADP-ribosylglutamate] hydrolase Neighboring gene DUF835 domain-containing protein Neighboring gene amidohydrolase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000961.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of a core domain of stomatin from Pyrococcus horikoshii Illustrates a novel trimeric and coiled-coil fold. Yokoyama H, et al. J Mol Biol, 2008 Feb 22. PMID 18182167
  2. Structural and biochemical analysis of a thermostable membrane-bound stomatin-specific protease. Yokoyama H, et al. J Synchrotron Radiat, 2013 Nov. PMID 24121343, Free PMC Article
  3. Crystal structure of a membrane stomatin-specific protease in complex with a substrate peptide. Yokoyama H, et al. Biochemistry, 2012 May 8. PMID 22475127
  4. A novel thermostable membrane protease forming an operon with a stomatin homolog from the hyperthermophilic archaebacterium Pyrococcus horikoshii. Yokoyama H, et al. J Biol Chem, 2005 Feb 25. PMID 15611110
  5. Slipins: ancient origin, duplication and diversification of the stomatin protein family. Green JB, et al. BMC Evol Biol, 2008 Feb 11. PMID 18267007, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Study reports the crystal structure of a stomatin ortholog, the core domain of the p-stomatin PH1511p,PhSto(CD) forms a novel homotrimeric structure.
    Title: Crystal structure of a core domain of stomatin from Pyrococcus horikoshii Illustrates a novel trimeric and coiled-coil fold.
  2. sites of cleavage by PH1510 are rich in hydrophobic residues; PH1510 probably functions in cooperation with PH1511. It is hypothesized that the cleavage of the stomatin-homolog PH1511 by the PH1510 protease causes an ion channel to open
    Title: A novel thermostable membrane protease forming an operon with a stomatin homolog from the hyperthermophilic archaebacterium Pyrococcus horikoshii.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
slipin family protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000961.1 Reference assembly

    Range
    1345253..1346053
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010885588.1 slipin family protein [Pyrococcus horikoshii]

    See identical proteins and their annotated locations for WP_010885588.1

    UniProtKB/Swiss-Prot
    O59180
    UniProtKB/TrEMBL
    A0A832SXK5
    Conserved Domains (2) summary
    smart00244
    Location:23 → 176
    PHB; prohibitin homologues
    cd08826
    Location:55 → 232
    SPFH_eoslipins_u1; Uncharacterized prokaryotic subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O59180.1

Gene LinkOut

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