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jag1b - jagged canonical Notch ligand 1b

Predicted to enable Notch binding activity. Acts upstream of or within several processes, including exocrine pancreas development; face morphogenesis; and inner ear development. Predicted to be located in plasma membrane. Is expressed in several structures, including digestive system; endocrine system; nervous system; otic vesicle; and pharyngeal arch. Human ortholog(s) of this gene implicated in Alagille syndrome; Charcot-Marie-Tooth disease; congenital heart disease; multiple sclerosis; and tetralogy of Fallot. Orthologous to human JAG1 (jagged canonical Notch ligand 1). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa