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RALYL RALY RNA binding protein like [ Homo sapiens (human) ]

Gene ID: 138046, updated on 27-Nov-2024

Summary

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Official Symbol
RALYLprovided by HGNC
Official Full Name
RALY RNA binding protein likeprovided by HGNC
Primary source
HGNC:HGNC:27036
See related
Ensembl:ENSG00000184672 MIM:614648; AllianceGenome:HGNC:27036
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HNRPCL3
Summary
Enables identical protein binding activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in brain (RPKM 3.1), adrenal (RPKM 2.1) and 3 other tissues See more
Orthologs
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Genomic context

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See RALYL in Genome Data Viewer
Location:
8q21.2
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (84182787..84921844)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (84620396..85359723)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (85095022..85834079)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124901968 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:84932099-84932600 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:84932601-84933100 Neighboring gene tropomyosin alpha-3 chain-like Neighboring gene tropomyosin 3 pseudogene 3 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:85202593-85203155 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:85336945-85337514 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr8:85532990-85533510 Neighboring gene Sharpr-MPRA regulatory region 11463 Neighboring gene RNA, U6 small nuclear 1040, pseudogene Neighboring gene PSMC2 pseudogene 2 Neighboring gene glucosamine-phosphate N-acetyltransferase 1 pseudogene Neighboring gene uncharacterized LOC124902092 Neighboring gene joining chain of multimeric IgA and IgM pseudogene 1 Neighboring gene ACTB pseudogene 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. A novel cDNA encodes a putative hRALY-like protein, hRALYL. Ji CN, et al. Mol Biol Rep, 2003 Mar. PMID 12688537
  2. Over-expression of RALYL suppresses the progression of ovarian clear cell carcinoma through inhibiting MAPK and CDH1 signaling pathways. Xia Y, et al. Int J Med Sci, 2021. PMID 33437214, Free PMC Article
  3. Exploring the role of RALYL in Alzheimer's disease reserve by network-based approaches. Zhang Y, et al. Alzheimers Res Ther, 2020 Dec 9. PMID 33298176, Free PMC Article
  4. Screening of LRRK2 interactants by yeast 2-hybrid analysis. Zheng XY, et al. Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2008 Oct. PMID 19001729
  5. Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases. Cobb J, et al. Pharmacogenomics J, 2014 Aug. PMID 24709693, Free PMC Article

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Over-expression of RALYL suppresses the progression of ovarian clear cell carcinoma through inhibiting MAPK and CDH1 signaling pathways.
    Title: Over-expression of RALYL suppresses the progression of ovarian clear cell carcinoma through inhibiting MAPK and CDH1 signaling pathways.
  2. Exploring the role of RALYL in Alzheimer's disease reserve by network-based approaches.
    Title: Exploring the role of RALYL in Alzheimer's disease reserve by network-based approaches.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RNA-binding Raly-like protein
Names
heterogeneous nuclear ribonucleoprotein C-like 3
hnRNP core protein C-like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100391.3 → NP_001093861.1  RNA-binding Raly-like protein isoform 1

    See identical proteins and their annotated locations for NP_001093861.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    Consensus CDS
    CCDS55252.1
    UniProtKB/TrEMBL
    B3KSX3
    Related
    ENSP00000430128.1, ENST00000517638.5
    Conserved Domains (2) summary
    pfam10779
    Location:212 → 257
    XhlA; Haemolysin XhlA
    cl17169
    Location:28 → 110
    RRM_SF; RNA recognition motif (RRM) superfamily

  2. NM_001100392.3 → NP_001093862.1  RNA-binding Raly-like protein isoform 2

    See identical proteins and their annotated locations for NP_001093862.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. Variants 2 through 4 encode the same isoform (2), which has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816
    Consensus CDS
    CCDS55253.1
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2
    UniProtKB/TrEMBL
    B3KSX3
    Related
    ENSP00000430394.1, ENST00000522455.5
    Conserved Domains (2) summary
    pfam10779
    Location:199 → 244
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  3. NM_001100393.3 → NP_001093863.1  RNA-binding Raly-like protein isoform 2

    See identical proteins and their annotated locations for NP_001093863.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. Variants 2 through 4 encode the same isoform (2), which has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    Consensus CDS
    CCDS55253.1
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2
    UniProtKB/TrEMBL
    B3KSX3
    Related
    ENSP00000428667.1, ENST00000521695.5
    Conserved Domains (2) summary
    pfam10779
    Location:199 → 244
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  4. NM_001287243.3 → NP_001274172.1  RNA-binding Raly-like protein isoform 3

    See identical proteins and their annotated locations for NP_001274172.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and the 5' coding region, initiates translation at a downstream start codon and lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 3, which is shorter than isoform 1.
    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    Consensus CDS
    CCDS75760.1
    UniProtKB/TrEMBL
    B3KSX3, B3KT61
    Related
    ENSP00000430065.1, ENST00000518566.5
    Conserved Domains (3) summary
    COG0724
    Location:12 → 190
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam10779
    Location:188 → 233
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  5. NM_001287244.2 → NP_001274173.1  RNA-binding Raly-like protein isoform 4

    See identical proteins and their annotated locations for NP_001274173.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) contains an alternate 5' terminal exon resulting in a novel 5' UTR and 5' coding region, compared to variant 1. It encodes isoform 4, which is shorter and has a distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AC009901, AC087368
    Consensus CDS
    CCDS75761.1
    UniProtKB/Swiss-Prot
    Q86SE5
    Related
    ENSP00000428807.1, ENST00000523850.5
    Conserved Domains (1) summary
    pfam10779
    Location:126 → 171
    XhlA; Haemolysin XhlA

  6. NM_001354305.2 → NP_001341234.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816
    Consensus CDS
    CCDS55253.1
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2
    UniProtKB/TrEMBL
    B3KSX3
    Conserved Domains (2) summary
    pfam10779
    Location:199 → 244
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  7. NM_001354306.2 → NP_001341235.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    Consensus CDS
    CCDS55253.1
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2
    UniProtKB/TrEMBL
    B3KSX3
    Conserved Domains (2) summary
    pfam10779
    Location:199 → 244
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  8. NM_001354307.2 → NP_001341236.1  RNA-binding Raly-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    Consensus CDS
    CCDS75760.1
    UniProtKB/TrEMBL
    B3KSX3, B3KT61
    Conserved Domains (3) summary
    COG0724
    Location:12 → 190
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam10779
    Location:188 → 233
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  9. NM_001354308.2 → NP_001341237.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC027043, AC087368, AC092699
    Consensus CDS
    CCDS55253.1
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2
    UniProtKB/TrEMBL
    B3KSX3
    Conserved Domains (2) summary
    pfam10779
    Location:199 → 244
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  10. NM_001354309.2 → NP_001341238.1  RNA-binding Raly-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    Consensus CDS
    CCDS75760.1
    UniProtKB/TrEMBL
    B3KSX3, B3KT61
    Conserved Domains (3) summary
    COG0724
    Location:12 → 190
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam10779
    Location:188 → 233
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  11. NM_001354310.2 → NP_001341239.1  RNA-binding Raly-like protein isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC087368
    Conserved Domains (1) summary
    pfam10779
    Location:111 → 156
    XhlA; Haemolysin XhlA

  12. NM_001354311.2 → NP_001341240.1  RNA-binding Raly-like protein isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    UniProtKB/TrEMBL
    B3KSX3
    Conserved Domains (1) summary
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  13. NM_001354312.2 → NP_001341241.1  RNA-binding Raly-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816
    Consensus CDS
    CCDS75760.1
    UniProtKB/TrEMBL
    B3KSX3, B3KT61
    Conserved Domains (3) summary
    COG0724
    Location:12 → 190
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam10779
    Location:188 → 233
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  14. NM_001354313.2 → NP_001341242.1  RNA-binding Raly-like protein isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    UniProtKB/TrEMBL
    B3KSX3
    Conserved Domains (1) summary
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  15. NM_001354314.2 → NP_001341243.1  RNA-binding Raly-like protein isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    UniProtKB/TrEMBL
    B3KSX3
    Conserved Domains (2) summary
    COG1579
    Location:195 → 250
    COG1579; Predicted nucleic acid-binding protein, contains Zn-ribbon domain [General function prediction only]
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  16. NM_001354315.2 → NP_001341244.1  RNA-binding Raly-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    Consensus CDS
    CCDS75760.1
    UniProtKB/TrEMBL
    B3KSX3, B3KT61
    Conserved Domains (3) summary
    COG0724
    Location:12 → 190
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam10779
    Location:188 → 233
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  17. NM_001354316.2 → NP_001341245.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816
    Consensus CDS
    CCDS55253.1
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2
    UniProtKB/TrEMBL
    B3KSX3
    Conserved Domains (2) summary
    pfam10779
    Location:199 → 244
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  18. NM_001354317.2 → NP_001341246.1  RNA-binding Raly-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816
    Consensus CDS
    CCDS75760.1
    UniProtKB/TrEMBL
    B3KSX3, B3KT61
    Conserved Domains (3) summary
    COG0724
    Location:12 → 190
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam10779
    Location:188 → 233
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  19. NM_001354318.2 → NP_001341247.1  RNA-binding Raly-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    Consensus CDS
    CCDS75760.1
    UniProtKB/TrEMBL
    B3KSX3, B3KT61
    Conserved Domains (3) summary
    COG0724
    Location:12 → 190
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam10779
    Location:188 → 233
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  20. NM_001354319.2 → NP_001341248.1  RNA-binding Raly-like protein isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816
    UniProtKB/TrEMBL
    B3KSX3
    Conserved Domains (1) summary
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  21. NM_001354320.2 → NP_001341249.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    Consensus CDS
    CCDS55253.1
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2
    UniProtKB/TrEMBL
    B3KSX3
    Conserved Domains (2) summary
    pfam10779
    Location:199 → 244
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  22. NM_001354321.2 → NP_001341250.1  RNA-binding Raly-like protein isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    UniProtKB/TrEMBL
    B3KSX3
    Conserved Domains (3) summary
    COG0724
    Location:25 → 203
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam10779
    Location:201 → 246
    XhlA; Haemolysin XhlA
    cl17169
    Location:28 → 110
    RRM_SF; RNA recognition motif (RRM) superfamily

  23. NM_001354322.2 → NP_001341251.1  RNA-binding Raly-like protein isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    Conserved Domains (2) summary
    COG0724
    Location:25 → 203
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cl17169
    Location:28 → 110
    RRM_SF; RNA recognition motif (RRM) superfamily

  24. NM_001354323.2 → NP_001341252.1  RNA-binding Raly-like protein isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    UniProtKB/TrEMBL
    B3KSX3
    Conserved Domains (1) summary
    cl17169
    Location:28 → 110
    RRM_SF; RNA recognition motif (RRM) superfamily

  25. NM_001354325.2 → NP_001341254.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    Consensus CDS
    CCDS55253.1
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2
    UniProtKB/TrEMBL
    B3KSX3
    Conserved Domains (2) summary
    pfam10779
    Location:199 → 244
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  26. NM_001413300.1 → NP_001400229.1  RNA-binding Raly-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    UniProtKB/TrEMBL
    B3KT61

  27. NM_001413301.1 → NP_001400230.1  RNA-binding Raly-like protein isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816

  28. NM_001413302.1 → NP_001400231.1  RNA-binding Raly-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816
    UniProtKB/TrEMBL
    B3KT61

  29. NM_001413303.1 → NP_001400232.1  RNA-binding Raly-like protein isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368

  30. NM_001413304.1 → NP_001400233.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2

  31. NM_001413305.1 → NP_001400234.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2

  32. NM_001413306.1 → NP_001400235.1  RNA-binding Raly-like protein isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368

  33. NM_001413307.1 → NP_001400236.1  RNA-binding Raly-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816
    UniProtKB/TrEMBL
    B3KT61

  34. NM_001413308.1 → NP_001400237.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2

  35. NM_001413309.1 → NP_001400238.1  RNA-binding Raly-like protein isoform 14

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368

  36. NM_001413310.1 → NP_001400239.1  RNA-binding Raly-like protein isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368

  37. NM_001413311.1 → NP_001400240.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2

  38. NM_001413312.1 → NP_001400241.1  RNA-binding Raly-like protein isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368

  39. NM_001413313.1 → NP_001400242.1  RNA-binding Raly-like protein isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368

  40. NM_001413314.1 → NP_001400243.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2

  41. NM_001413315.1 → NP_001400244.1  RNA-binding Raly-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    UniProtKB/TrEMBL
    B3KT61

  42. NM_001413316.1 → NP_001400245.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2

  43. NM_001413318.1 → NP_001400247.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2

  44. NM_001413319.1 → NP_001400248.1  RNA-binding Raly-like protein isoform 20

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368

  45. NM_001413320.1 → NP_001400249.1  RNA-binding Raly-like protein isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368

  46. NM_001413321.1 → NP_001400250.1  RNA-binding Raly-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2

  47. NM_001413322.1 → NP_001400251.1  RNA-binding Raly-like protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    UniProtKB/TrEMBL
    B3KT61

  48. NM_001413323.1 → NP_001400252.1  RNA-binding Raly-like protein isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368, AC103816

  49. NM_001413324.1 → NP_001400253.1  RNA-binding Raly-like protein isoform 18

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC087368
    Related
    ENSP00000428310.1, ENST00000521376.1

  50. NM_001413329.1 → NP_001400258.1  RNA-binding Raly-like protein isoform 19

    Status: VALIDATED

    Source sequence(s)
    AC009901, AC087368

  51. NM_173848.7 → NP_776247.3  RNA-binding Raly-like protein isoform 2

    See identical proteins and their annotated locations for NP_776247.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. Variants 2 through 4 encode the same isoform (2), which has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AC009901, AC012400, AC027043, AC087368
    Consensus CDS
    CCDS55253.1
    UniProtKB/Swiss-Prot
    B3KTH2, G3V129, Q6ZW87, Q86SE5, Q8N1C2
    UniProtKB/TrEMBL
    B3KSX3
    Related
    ENSP00000430367.1, ENST00000521268.6
    Conserved Domains (2) summary
    pfam10779
    Location:199 → 244
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    84182787..84921844
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024447066.2 → XP_024302834.1  RNA-binding Raly-like protein isoform X1

    UniProtKB/TrEMBL
    B3KSX3, B3KT61
    Conserved Domains (3) summary
    COG0724
    Location:12 → 190
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam10779
    Location:188 → 233
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

  2. XM_047421387.1 → XP_047277343.1  RNA-binding Raly-like protein isoform X4

  3. XM_024447070.2 → XP_024302838.1  RNA-binding Raly-like protein isoform X6

    Conserved Domains (1) summary
    pfam04111
    Location:90 → 146
    APG6; Autophagy protein Apg6

  4. XM_011517462.4 → XP_011515764.1  RNA-binding Raly-like protein isoform X3

    Conserved Domains (2) summary
    COG0724
    Location:12 → 190
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cl17169
    Location:20 → 88
    RRM_SF; RNA recognition motif (RRM) superfamily

  5. XM_024447069.2 → XP_024302837.1  RNA-binding Raly-like protein isoform X5

    Conserved Domains (1) summary
    pfam04111
    Location:98 → 154
    APG6; Autophagy protein Apg6

  6. XM_024447068.2 → XP_024302836.1  RNA-binding Raly-like protein isoform X2

    Conserved Domains (2) summary
    COG0724
    Location:25 → 203
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12605
    Location:33 → 101
    RRM_RALYL; RNA recognition motif in vertebrate RNA-binding Raly-like protein (RALYL)

  7. XM_024447065.2 → XP_024302833.1  RNA-binding Raly-like protein isoform X1

    UniProtKB/TrEMBL
    B3KSX3, B3KT61
    Conserved Domains (3) summary
    COG0724
    Location:12 → 190
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam10779
    Location:188 → 233
    XhlA; Haemolysin XhlA
    cl17169
    Location:15 → 97
    RRM_SF; RNA recognition motif (RRM) superfamily

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    84620396..85359723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054359791.1 → XP_054215766.1  RNA-binding Raly-like protein isoform X1

    UniProtKB/TrEMBL
    B3KT61

  2. XM_054359794.1 → XP_054215769.1  RNA-binding Raly-like protein isoform X4

  3. XM_054359796.1 → XP_054215771.1  RNA-binding Raly-like protein isoform X6

  4. XM_054359793.1 → XP_054215768.1  RNA-binding Raly-like protein isoform X3

  5. XM_054359795.1 → XP_054215770.1  RNA-binding Raly-like protein isoform X5

  6. XM_054359792.1 → XP_054215767.1  RNA-binding Raly-like protein isoform X2

  7. XM_054359790.1 → XP_054215765.1  RNA-binding Raly-like protein isoform X1

    UniProtKB/TrEMBL
    B3KT61
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q86SE5.2 GenPept UniProtKB/Swiss-Prot:Q86SE5

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