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LOC132411470 STARR-positive B cell enhancer ABC_E6436 [ Mus musculus (house mouse) ]

Gene ID: 132411470, updated on 10-Feb-2024

Summary

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Gene symbol
LOC132411470
Gene description
STARR-positive B cell enhancer ABC_E6436
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
This genomic region was identified as a putative B cell regulatory element by FAIRE-seq (formaldehyde-assisted isolation of regulatory elements sequencing), and was validated as an enhancer by STARR-seq (self-transcribing active regulatory region sequencing) in lipopolysaccharide-activated mouse splenic B cells. [provided by RefSeq, Oct 2023]
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Genomic context

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See LOC132411470 in Genome Data Viewer
Location:
chromosome: 6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (70768948..70769249)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin kappa chain complex Neighboring gene STARR-positive B cell enhancer ABC_E11318 Neighboring gene STARR-positive B cell enhancer ABC_E2193 Neighboring gene STARR-positive B cell enhancer mm9_chr6:70694043-70694344 Neighboring gene STARR-positive B cell enhancer mm9_chr6:70702533-70702834 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:70712736-70712889 Neighboring gene STARR-seq mESC enhancer starr_16238 Neighboring gene STARR-seq mESC enhancer starr_16241 Neighboring gene STARR-positive B cell enhancer mm9_chr6:70761912-70762213 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:70764223-70764410 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:70765584-70765767 Neighboring gene STARR-seq mESC enhancer starr_16242 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:70779525-70779708 Neighboring gene predicted gene, 30211 Neighboring gene predicted gene, 30331 Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 3 Neighboring gene predicted gene, 23346 Neighboring gene immunoglobulin kappa constant Neighboring gene ribose 5-phosphate isomerase A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene regulatory networks STARR-ing B cells. Martínez de Paz A, et al. Nat Immunol, 2020 Feb. PMID 31873293, Free PMC Article
  2. Charting the cis-regulome of activated B cells by coupling structural and functional genomics. Chaudhri VK, et al. Nat Immunol, 2020 Feb. PMID 31873292

GeneRIFs: Gene References Into Functions

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_235328.1 

    Range
    101..402
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    70768948..70769249
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version