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LOC131338676 STARR-seq mESC enhancer starr_08639 [ Mus musculus (house mouse) ]

Gene ID: 131338676, updated on 10-Feb-2024

Summary

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Gene symbol
LOC131338676
Gene description
STARR-seq mESC enhancer starr_08639
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
This genomic region includes an enhancer that was validated by the STARR-seq (self-transcribing active regulatory region sequencing) reporter assay in metastable (SL) mouse embryonic stem cells, where it was defined as a C1 class enhancer that overlaps an active chromatin signature. Five subregions were identified as putative B cell regulatory elements by FAIRE-seq (formaldehyde-assisted isolation of regulatory elements sequencing), and were validated as enhancers by STARR-seq in lipopolysaccharide-activated mouse splenic B cells. [provided by RefSeq, Sep 2023]
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Genomic context

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See LOC131338676 in Genome Data Viewer
Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (105799181..105802908)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RAS-related protein 1a Neighboring gene STARR-positive B cell enhancer ABC_E10203 Neighboring gene STARR-positive B cell enhancer ABC_E11208 Neighboring gene STARR-seq mESC enhancer starr_08637 Neighboring gene predicted gene 5547 Neighboring gene STARR-seq mESC enhancer starr_08638 Neighboring gene transmembrane and immunoglobulin domain containing 3 Neighboring gene STARR-positive B cell enhancer ABC_E9566 Neighboring gene STARR-positive B cell enhancer ABC_E9567 Neighboring gene RIKEN cDNA I830077J02 gene Neighboring gene adenosine A3 receptor Neighboring gene STARR-seq mESC enhancer starr_08641

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene regulatory networks STARR-ing B cells. Martínez de Paz A, et al. Nat Immunol, 2020 Feb. PMID 31873293, Free PMC Article
  2. Charting the cis-regulome of activated B cells by coupling structural and functional genomics. Chaudhri VK, et al. Nat Immunol, 2020 Feb. PMID 31873292
  3. STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells. Peng T, et al. Genome Biol, 2020 Sep 10. PMID 32912294, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • STARR-positive B cell enhancer ABC_E10204
  • STARR-positive B cell enhancer ABC_E1025
  • STARR-positive B cell enhancer ABC_E420
  • STARR-positive B cell enhancer ABC_E6097
  • STARR-positive B cell enhancer ABC_E6098

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_208237.2 

    Range
    101..3828
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    105799181..105802908
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version