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LOC130064132 ATAC-STARR-seq lymphoblastoid active region 14419 [ Homo sapiens (human) ]

Gene ID: 130064132, updated on 12-Sep-2024

Summary

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Gene symbol
LOC130064132
Gene description
ATAC-STARR-seq lymphoblastoid active region 14419
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC130064132 in Genome Data Viewer
Location:
chromosome: 19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (29730692..29730741)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (32256433..32256482)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (30221599..30221648)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:30156127-30156680 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:30156681-30157234 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14411 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14412 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14413 Neighboring gene pleckstrin homology and FYVE domain containing 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:30181190-30181742 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:30181743-30182294 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14415 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14416 Neighboring gene chromosome 19 open reading frame 12 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10465 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14417 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14418 Neighboring gene uncharacterized LOC107985345 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:30219444-30219638 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14420 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30236313-30236812 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30235811-30236312 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30248109-30248688 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30248689-30249267 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_50922 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:30283256-30283456 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10466 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10467 Neighboring gene cyclin E1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14421 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10468 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10469 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14422 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30348658-30349496 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30349497-30350334 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10470 Neighboring gene Sharpr-MPRA regulatory region 11671 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10472 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:30373138-30373673 Neighboring gene peptidylprolyl isomerase A pseudogene 58

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_198549.1 

    Range
    101..150
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    29730692..29730741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    32256433..32256482
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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