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LOC130006956 ATAC-STARR-seq lymphoblastoid active region 5663 [ Homo sapiens (human) ]

Gene ID: 130006956, updated on 12-Sep-2024

Summary

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Gene symbol
LOC130006956
Gene description
ATAC-STARR-seq lymphoblastoid active region 5663
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC130006956 in Genome Data Viewer
Location:
chromosome: 11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (121655837..121656046)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (121682188..121682397)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (121526546..121526755)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5649 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5650 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5651 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4003 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5655 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4004 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5652 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5653 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5654 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4005 Neighboring gene SORL1 antisense RNA 1 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:121336477-121337676 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5657 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5658 Neighboring gene uncharacterized LOC105369535 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5659 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:121368848-121369348 Neighboring gene sortilin related receptor 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:121421721-121422920 Neighboring gene SORL1 eExon liver enhancer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5660 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:121441955-121442454 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5661 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:121441453-121441954 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4006 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5662 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:121465964-121467163 Neighboring gene Sharpr-MPRA regulatory region 6864 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr11:121507637-121508302 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr11:121508303-121508966 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr11:121514837-121515520 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:121543162-121543662 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:121559556-121560755 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5664 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:121673071-121673918 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:121694789-121695360 Neighboring gene uncharacterized LOC107984402 Neighboring gene VISTA enhancer hs872 Neighboring gene RNA, U6 small nuclear 256, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_186400.1 

    Range
    101..310
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    121655837..121656046
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    121682188..121682397
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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