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LOC130002946 ATAC-STARR-seq lymphoblastoid silent region 20476 [ Homo sapiens (human) ]

Gene ID: 130002946, updated on 12-Sep-2024

Summary

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Gene symbol
LOC130002946
Gene description
ATAC-STARR-seq lymphoblastoid silent region 20476
Gene type
biological region
Feature type(s)
regulatory: silencer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as a silencer based on its ability to repress an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC130002946 in Genome Data Viewer
Location:
chromosome: 9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (134135423..134135592)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (146349158..146349327)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (137000545..137000714)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene bromodomain containing 3 Neighboring gene uncharacterized LOC100130548 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:136924735-136925476 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:136927711-136928622 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20474 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20475 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr9:136956997-136957776 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr9:136957777-136958556 Neighboring gene ARF GTPase 4 pseudogene 1 Neighboring gene MPRA-validated peak7340 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:136991223-136992104 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:136992105-136992986 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:136994027-136994872 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:136994873-136995716 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:136997435-136998004 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29270 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:137001261-137002185 Neighboring gene WDR5 divergent transcript Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:137016988-137017508 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:137017509-137018028 Neighboring gene WD repeat domain 5 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:137028703-137029668 Neighboring gene uncharacterized LOC124902297 Neighboring gene RNA, U6atac small nuclear Neighboring gene uncharacterized LOC124902298 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29272 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29273 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:137095569-137096070 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:137096071-137096570

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_182392.1 

    Range
    101..270
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    134135423..134135592
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    146349158..146349327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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