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LOC130000442 ATAC-STARR-seq lymphoblastoid active region 27409 [ Homo sapiens (human) ]

Gene ID: 130000442, updated on 12-Sep-2024

Summary

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Gene symbol
LOC130000442
Gene description
ATAC-STARR-seq lymphoblastoid active region 27409
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC130000442 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (58411427..58411476)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (58832546..58832595)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (59323986..59324035)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986945 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr8:59108481-59109680 Neighboring gene VISTA enhancer hs1364 Neighboring gene long intergenic non-protein coding RNA 3133 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27407 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:59282662-59283206 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:59304090-59304590 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:59304591-59305091 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:59308925-59309426 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:59309427-59309926 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27408 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27410 Neighboring gene UBX domain protein 2B Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:59350272-59350772 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:59350773-59351273 Neighboring gene PTPN11 pseudogene 2 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr8:59404317-59405516 Neighboring gene CYP7A1 5' regulatory region Neighboring gene cytochrome P450 family 7 subfamily A member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_179888.1 

    Range
    101..150
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    58411427..58411476
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    58832546..58832595
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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